By Kim Borges

Jenny Walker can immediately spot the signs.

People who say they’ve forgotten their glasses when they’re asked to read aloud. Or who always order without looking at the menu.

One in every five Americans struggles with literacy; and 54 percent of people read at below a sixth-grade level.

“Imagine being at a first grade reading level and having second-grade student as a child,” said Walker. “That’s what gets me out of bed in the morning and what keeps me up at night.”

Literacy is an issue offering anyone valid cause for concern given lower reading rates are estimated to cost the U.S. $200 billion in safety and health issues and two-plus trillion dollars in lost productivity each year.

Walker has been on a personal mission to advance literacy from her early public school teaching days to her current role as executive director of the Texarkana-based nonprofit and Regions Bank customer Literacy Texas. But she’s the first to tell you no one can do this work alone.

That’s why Walker and her team collaborate with 300-plus fellow nonprofits and government agencies across the Lone Star State, including the Literacy County of Bowie and Miller Counties and 100 Families, two Regions Bank community partners. Walker formerly led the first nonprofit and helped establish the second.

Our great network of community partners and corporate partners like Regions Bank offer the support we need. And there’s a really big need in Texas for the work we’re doing.

“Our organization serves as a backbone of support,” explained Walker of Literacy Texas’s role connecting and equipping adult and family literacy programs through resources, training, networking and advocacy. “Our great network of community partners and corporate partners like Regions Bank offer the support we need. And there’s a really big need in Texas for the work we’re doing.”

How big?

“Texas is at a 28 percent level one for reading, and 40 percent of our population reads on a third-grade level,” said Walker. “That means people can put together short passages of text, but struggle with completing basic forms like job applications, medical history forms and back to school packets for their children.”

Just eight months into the job, Walker is already implementing her vision to address those struggles.

We also want to help them with life skills; we’re focused on providing holistic support. If we didn’t pick up those pieces, no one else would.

Jenny Walker

“We’re helping people develop workforce skills like writing resumes,” she said. “We also want to help them with life skills; we’re focused on providing holistic support. If we didn’t pick up those pieces, no one else would.”

The greatest challenge Walker and her team are working to resolve?

The digital divide – from both a navigation and a geographical perspective.

“We’re helping improve computer and digital literacy and getting out to our rural communities to connect people with broadband technology,” Walker said. “So many forms like food benefit applications are online now. Some of us take technology for granted because we use it every day, but a large part of the population does not. Vocabulary terms like ‘upload’ can be challenging and intimidating. We do a really good job of making things more intuitive.”

Walker understands where Literacy Texas’s clients come from – literally. She proudly calls on her hometown roots advocating for the organization at events like National Adult Education and Family Literacy Week in Washington, D.C., in September.

Through the support of our community partners, we’re not only contributing to an educated workforce, we are empowering people to dream – some of them for the first time in their lives.

Jenny Walker

“Look at little ol’ me from Texarkana,” Walker said about making the trip. “I think people in small towns sometimes feel stuck; I’ve felt that before. But I’ve learned I’m not stuck. I’ve learned you can do big things in a small town. I don’t allow being from a small town to hold me back from taking advantage of big opportunities.”

It’s the same message she imparts to Literacy Texas’s nonprofit partners and those they serve.

“Early on, I asked myself, ‘How can we support those we serve with our small staff and their big dreams?’” she said. “That’s where things like computer and digital literacy come in; they’re powerful tools we can share and help people leverage. Through the support of our community partners, we’re not only contributing to an educated workforce, we are empowering people to dream – some of them for the first time in their lives.”

Check out these Regions Bank and Regions Foundation community partners promoting youth literacy:

Read, Write and Rock OnTurn the PageLoving to Learn: Regions Foundation Awards Grants to ReadyKids! ReadingPals

December 16, 2024 /3BL/ – To escape hostilities, more than 1 million people in Syria have fled their homes amid widespread humanitarian challenges after the government was overthrown.

“After more than 13 years of conflict, Syria is a country with more than 16 million people in need of urgent assistance and with very high levels of food insecurity. The situation was already very dire before the latest events, and before the recent influx of families fleeing the conflict in Lebanon to find refuge in Syria,” said Elise Madouche, Action Against Hunger’s Country Director in Syria.

90% of Syria’s population lives under the poverty line and with winter quickly approaching, families face new risks.

“In some areas, access to food and water has been hampered. Humanitarian interventions are more urgent than ever, especially with new displacements and harsh weather,” Madouche said. “Since we can only expect needs may increase, the important thing now is to provide shelter and safety for the most vulnerable individuals in both the host and displaced communities.”

Action Against Hunger has been working in Syria since 2008. The organization’s multi-sectoral programs focus on providing maternal and childcare, reproductive health services, water supply and sanitation, and support to famers and their families.

“All non-governmental organizations had to put on hold their activities because of the situation,” said Madouche. “It is important that humanitarian organizations like ours resume the work of all activities that we have been implementing for years, to continue supporting all vulnerable communities in Syria.”

Action Against Hunger teams in Syria are fully prepared to resume operations put on hold and scale up all programs and respond to unfolding needs.

“Action Against Hunger’s commitment remains steadfast as we continue to address the urgent needs of the population and support their path towards a stable and peaceful future,” said Madouche.

About Action Against Hunger

Action Against Hunger leads the global movement to end hunger. We innovate solutions, advocate for change, and reach 21 million people every year with proven hunger prevention and treatment programs. As a nonprofit that works across 59 countries, our 8,900 dedicated staff members partner with communities to address the root causes of hunger, including climate change, conflict, inequity, and emergencies. We strive to create a world free from hunger, for everyone, for good.

Originally published in Mary Kay’s 2024 Sustainability Report

As a global sustainability advocate, Mary Kay continues to make strides in corporate water stewardship at its manufacturing sites around the world and to engage for healthy oceans through work in partnership and advocacy for women leaders in conservation.

WATER AT MARY KAY

Water, a fundamental and precious resource, is at the center of sustainability and crucial to Mary Kay’s manufacturing process. As a global sustainability advocate, the company is committed to reducing water utilization at its global manufacturing facilities in Lewisville, Texas and Hangzhou, China.

Mary Kay has a commitment to monitor our water usage as we work cross-functionally to continually improve on our comprehensive water dashboard to automate the collection of water usage data at our manufacturing site. Our goal is to improve accuracy and identify other advancements while being a responsible water steward in our local community.

100,000 GALLONS SAVED MONTHLY1
In August 2023, Mary Kay implemented an improvement (shutting off sample ports) that is projected to save approximately 100,000 gallons per month in our R3 site. 

572,000 GALLONS SAVED ANNUALLY
Between 2021 and 2023, Mary Kay optimized several manufacturing cleaning processes which resulted in saving a projected 572,000 gallons of water each year based on production forecast in our R3 site. 

Global Alignment: Mary Kay is a signatory to two crucial causes addressing global water challenges through corporate water stewardship: the CEO Water Mandate and the United Nations Global Compact’s Sustainable Ocean Principles.

OCEAN CONSERVATION: “SUPER REEFS”

For 36 years, Mary Kay has partnered with The Nature Conservancy (TNC) to tackle ocean health and coral reef awareness the world over. Through this long-standing partnership, Mary Kay supports the “Super Reefs” initiative which identifies, protects, and grows a global network of highly resilient coral reefs that can survive in a warming ocean.

The Super Reefs team brings together reef governments and communities with experts in ocean science, conservation, and management from Woods Hole Oceanographic Institution, Stanford University, and The Nature Conservancy, along with private sector support from Mary Kay. Several areas of interest have been identified including Hawaii, Palau, the Marshall Islands, and Belize.

37 YEARS OF PARTNERSHIP 100 CONSERVATION PROJECTS SUPPORTED WORLDWIDENEARLY 50% OF THE EARTH’S CORAL REEFS HAVE BEEN LOST TO DATE.

ADVOCACY FOR WOMEN LEADERS IN CONSERVATION

The panel “Putting Coral Reef Restoration at the Heart of Ocean Conservation Action” held during the Economist Impact’s 10th World Ocean Summit in Lisbon, Portugal, allowed Mary Kay to highlight women’s crucial role in ocean conservation and to showcase our partnership with The Nature Conservancy as a best practice of private sector engagement.

WATCH THE PANEL HERE

1 Methodology: These projected water savings are calculated by monitoring the data pulled from our flow meters installed and brought online in 2023 and forecasting the annual projections based on daily and weekly averages. We will continue to monitor water usage and forecast savings as projections are subject to change based on external factors such as demand.

Feature by Sophia Mendelsohn

The 29th UN Climate Conference (COP29) in Baku, Azerbaijan, aimed to advance a new climate finance goal and inspire stronger national climate commitments. While progress was made, the private sector must now play a pivotal role in turning these ambitions into actionable outcomes. Central to this effort is the energy transition, one of the key economic growth drivers of our time.

The energy transition is creating a profound shift across industries and global economies. Amplified by technological innovation and intense competition, it is reshaping sectors and shifting economies toward renewable energy. This change is not only an environmental necessity but also a catalyst for economic growth, challenging the traditional dominance of fossil fuels. With capital investments increasingly directed toward renewable energy infrastructure, investors are aligning their priorities with sustainability, signaling that profitability and environmental stewardship can coexist. Yet, the ongoing prominence of oil and gas underlines the complexity and scale of this transition.

In parallel, the circular economy is gaining momentum as businesses address the dual challenges of material scarcity and carbon reduction. At COP29, there was significant discussion about how a circular approach focused on rethinking supply chains, redesigning products, and optimizing resources could reduce dependency on finite materials while driving sustainable economic growth. By adopting circular economy principles, businesses can minimize waste and keep valuable materials in circulation, contributing to a more resilient and sustainable future.

The Role of Business in Transforming Climate Commitments into Tangible Outcomes 

One of the central discussions at COP29 was the need for harmonizing global standards for carbon reduction and accounting. Foreign policy players, along with the private sector, stressed the importance of mobilizing finance for sustainable capitalism. In particular, there was a call for clearer and standardized reporting frameworks to simplify the process and ensure transparency. One critical area was the importance of accurate data collection for carbon markets and product-level carbon accounting, which can help businesses engage consumers and reduce emissions.

There are three ways technology plays a pivotal role in addressing some of these challenges:

Sustainability data is available in every organization’s ERP system, so it’s time to start automating data collection and reporting processes to ease some of the regulatory burden.Companies should leverage IT spending to support sustainability initiatives, specifically by applying generative AI to optimize climate solutions and create circular products.Companies must shift focus on the carbon footprint of specific products to pinpoint areas with the most significant impact.

From Policy to Practice: How Technology and Global Standards Can Accelerate Climate Action 

Empowered by technology and guided by clear policies, businesses have a unique opportunity to bridge the gap between high-level climate commitments and actionable, on-the-ground strategies.

Central to this is aligning sustainability and financial priorities. Effective climate action demands collaboration between chief sustainability officers and chief financial officers, as climate change has evolved from an ethical and environmental issue to a pressing financial imperative.

To accelerate progress, we need globally harmonized policies, rigorous carbon accounting frameworks, and advanced technology solutions. By embedding AI-driven innovation, robust reporting standards, and actionable insights into business operations, we can ensure that COP events, such as COP29 in Baku, are remembered as turning points – not just discussions. While the challenges ahead are formidable, the opportunities for transformative action are even greater – and SAP is here to lead the way on a low-carbon, circular future.

Sophia Mendelsohn is chief sustainability and commercial officer at SAP.

December 16, 2024 /3BL/ – Lenovo is proud to announce that it has been awarded the Platinum Medal by EcoVadis, the leading global provider of business sustainability ratings. With a score of 85/100, this recognition places Lenovo in the top 1% of all companies rated by EcoVadis worldwide and underscores its ongoing commitment to sustainability.

This achievement also recognizes Lenovo as a Leader in Carbon Management, achieving the highest ranking in its category with a best-in-class greenhouse gas (GHG) management system and strong ambition for decarbonization. Lenovo has embedded sustainability into its global value chain, operations, and product innovation. With measured improvements across environmental responsibility, labor and human rights, ethics, and sustainable procurement, Lenovo continues to elevate its sustainability efforts in alignment to global standards.

“Being awarded a Platinum Medal by EcoVadis is a key milestone for Lenovo,” said Laura Quatela, Senior Vice President, Chief Legal & Corporate Responsibility Officer, Lenovo. “Our focus on collaboration, credibility, and accountability will continue to power us forward on our sustainability journey. We’re honored by this recognition and remain focused on the short-term and long-term goals ahead.”

Lenovo has made meaningful advancements in its sustainability strategy in past years, including committing to achieve net-zero greenhouse gas emissions by 2050. Lenovo was in the first group of companies to have its goals validated by the Science Based Targets initiative in January 2023. In January 2024 Lenovo maintained its AAA status on MSCI’s ranking and in September 2024 was awarded the strongest score in the IT industry for environmental and social achievements in the Hang Seng Corporate Sustainability Index, receiving an AA score overall. 

The EcoVadis score reflects the quality of a company’s sustainability management system at the time of the assessment. EcoVadis Medals and Badges recognize eligible companies that have completed the EcoVadis assessment process and demonstrated a relatively strong management system that addresses sustainability criteria with policies, actions, and significant results. More information on the EcoVadis assessment process can be found here

Read more about Lenovo’s Environmental, Social, and Governance performance in the FY2023/24 ESG Report.

About Lenovo

Lenovo is a US$57 billion revenue global technology powerhouse, ranked #248 in the Fortune Global 500, and serving millions of customers every day in 180 markets. Focused on a bold vision to deliver Smarter Technology for All, Lenovo has built on its success as the world’s largest PC company with a full-stack portfolio of AI-enabled, AI-ready, and AI-optimized devices (PCs, workstations, smartphones, tablets), infrastructure (server, storage, edge, high performance computing and software defined infrastructure), software, solutions, and services. Lenovo’s continued investment in world-changing innovation is building a more equitable, trustworthy, and smarter future for everyone, everywhere. Lenovo is listed on the Hong Kong stock exchange under Lenovo Group Limited (HKSE: 992) (ADR: LNVGY). To find out more visit https://www.lenovo.com, and read about the latest news via our  StoryHub.

CAMDEN, N.J., December 16, 2024 /3BL/ – Subaru of America, Inc., and its WinterFest partner, POWDR, today announced the return of the automaker’s annual mountain tour, Subaru WinterFest, the premier winter playground for music fans, skiers, snowboarders, and dog lovers alike. WinterFest will be arriving at six mountain destinations across the U.S. this winter.

Alan Bethke, Senior Vice President, Marketing at Subaru of America, Inc.: “WinterFest is one of our most highly anticipated events of the year, and we look forward to bringing the experience to some of the coolest mountain locations again this winter. For anyone seeking adventure, entertainment, and an opportunity to give back to charitable causes, WinterFest is the perfect combination to meet these priorities.”

Headlining artists including Grace Potter, The National Parks, The Travelin’ McCourys, Ashes to Amber, Shadowgrass, Into the Fog and more are set to perform this season’s tour along with incredible supporting acts.

“We’re thrilled to join forces once again with Subaru for the WinterFest series, promising attendees an unforgettable event this season,” said Meghan Matschke, Vice President of Partnerships at POWDR. “With an impressive lineup of musicians, activations with leading outdoor brands, and a deep commitment to the community, excitement is at an all-time high. Get ready to carve unforgettable memories with us on the slopes!”

As part of its commitment to being “More Than a Car Company,” WinterFest attendees who complete a lead form will be able to choose a non-profit charity partner for Subaru to make a $5 donation on their behalf, up to $10,000 per charity over the course of the tour. Organizations will include Operation Warm®, SheJumps, and Wasatch Backcountry Rescue. In addition, Subaru and POWDR have a joint community investment fund aligned with the values of the Subaru Love Promise and POWDR’s Play Forever commitment to support important community and environmental initiatives.

This year’s tour will include the automaker’s adventure-ready 2024 Subaru Crosstrek Wilderness and the2024 Subaru Solterra. Subaru ambassadors will be available to highlight features such as Harmon Kardon sound systems and more.

Guests will have access to a variety of WinterFest activities. Returning this year, the Americana-inspired Harman Kardon Warming Hut will provide WinterFest attendees with an opportunity to demo Harman Kardon’s latest portable Bluetooth products in a cozy and warm environment. Attendees can also check out the newest gear from acclaimed brands such as Thule, Nordica, 100%, Mammut, Luno, and Dynamic Wax, in addition to Wilderdog for their furry companions. Leave No Trace will also have experts available to inform people of ways to conserve the outdoors. Attendees can get an energy boost in the morning at the Wilderness Cafe with complimentary coffee from Alpine Start, and craft hot cocoa, served in a YETI mug along with Kate’s Real Food organic energy bars, (while supplies last). There will also be a Solo Stove Hangout Zone at every stop for guests to warm up by the fire and roast marshmallows for s’mores in the afternoon. Additionally, there will be daily giveaways of wonderful prizes from the automaker’s partners.

As a special treat for some lucky Subaru owners, some Subaru Winterfest events will feature exclusive ‘on-mountain’ experiences, intimate music sessions, VIP parking privileges and exclusive gifts (subject to availability).

The full schedule for Subaru WinterFest 2025 can be found below:

WeekendResortHeadline ArtistJanuary 31 – February 2Killington Resort, VT*The Travelin’ McCourysFebruary 21 – 23Copper Mountain Resort, COThe National ParksMarch 7 – 9Eldora Mountain Resort, COShadowgrassMarch 15 – 16Sierra-at-Tahoe Resort, CA*TBDApril 4 – 6Snowbird, UTAshes to AmberApril 11 – 13Mt. Bachelor, ORGrace Potter

*Killington and Sierra-at-Tahoe are not POWDR-owned or operated resorts. 

For more information on Subaru WinterFest locations, please visit www.subaruwinterfest.com and follow #SubaruWinterFest on social media.

About Subaru of America, Inc.

Subaru of America, Inc. (SOA) is an indirect wholly owned subsidiary of Subaru Corporation of Japan. Headquartered in Camden, N.J., the company markets and distributes Subaru vehicles, parts, and accessories through a network of about 640 retailers across the United States. All Subaru products are manufactured in zero-landfill plants, including Subaru of Indiana Automotive, Inc., the only U.S. automobile manufacturing plant designated a backyard wildlife habitat by the National Wildlife Federation. SOA is guided by the Subaru Love Promise, which is the company’s vision to show love and respect to everyone and to support its communities and customers nationwide. Over the past 20 years, SOA and the SOA Foundation have donated more than $320 million to causes the Subaru family cares about, and its employees have logged over 100,000 volunteer hours. Subaru is dedicated to being More Than a Car Company® and to making the world a better place. For additional information, visit media.subaru.com. Follow us on Facebook, Instagram, LinkedIn, TikTok, and YouTube.

About POWDR

POWDR is an adventure lifestyle company that inspires every human being with cool experiences in awesome places. POWDR’s awesome places include Copper Mountain and Eldora Mountain Resort in Colorado; Boreal Mountain Resort and Soda Springs in the Lake Tahoe region of California; Mt. Bachelor in Oregon; Snowbird in Utah; and SilverStar Mountain Resort in British Columbia, Canada. The company also fuels adventure through a collection of experiences from the mountains to the valleys including Sun Country Tours river rafting outfitter based in Oregon, Powderbird heli-adventure operator based out of Snowbird in Utah, Stovepipe lodging and concessions based in Death Valley National Park, and coming soon (2025), the Zion Lodge concessions based in Zion National Park. POWDR’s Woodward brand empowers and inspires the next generation of action sports enthusiasts through summer camps, mountain experiences, and mountain centers, incorporating dynamic programming and innovative environments at Woodward Park City in Utah, Woodward PA in Pennsylvania, Woodward Copper in Colorado, Woodward Tahoe and Woodward West in California.

POWDR is headquartered in Park City, UT. For more information, please visit: www.POWDR.com.

Contacts:

Diane Anton
Corporate Communications Manager
(856) 488-5093
danton@subaru.com

Adam Leiter
Corporate Communications Specialist
(856) 488-8668
aleiter@subaru.com

###

The 2024 United Nations Climate Change Conference – better known as the 29th meeting of the Council of the Parties (COP29) – wrapped up on November 24 in Baku, Azerbaijan with a mixed bag of new climate agreements but limited progress on commitments to finance the global clean energy transition. Looming over the meeting was the election victory by former President Trump and his pledge to pull the U.S. out of the 2015 Paris Agreement climate treaty for the second time.

In our Top Stories in this issue, we have several articles on the developments that came out of COP29 and what they mean for efforts to reduce carbon emissions worldwide.

ESG Today reported on a breakthrough agreement on the first day of the meetings to establish standards for the creation of carbon credits under Article 6.4 of the Paris Agreement. According to the report, the agreement is “key for advancing the establishment and growth of a global carbon market” and will “establish a market-based system for carbon credits… and accredit third-party verification bodies.” 
 Reuters reported on an agreement reached after two extra days of negotiations to adopt a global finance target of US$300 billion a year by 2035 to help developing nations cope with impacts of climate change. According to Reuters, the agreement was criticized by developing nations as falling “woefully insufficient” of what is needed. While the new target is three times higher than the previous target set in 2009 of $100 billion a year by 2020, Reuters noted, “that earlier goal was met two years late, in 2022” and that the new agreement includes a broader goal of raising $1.3 trillion a year by 2035, which is what “economists say matches the sum needed to address global warming.” 
 Allen Schaeffer of Engine Technology Forum wrote that discussions at COP29 appear to have been dominated by the impending change in the U.S. administration and anticipated reversal of support for the Paris Agreement. He does take an optimistic view that despite the upcoming collision between global climate agreements and the Trump administration, he expects “leaders in advanced engines and fuels to keep innovating their existing products and exploring new technologies and fuels like advanced renewable biofuels electrification, or hydrogen… because they know customers demand it and market competition ensures it.”

The mixed results coming from COP29 highlight the limitations faced by multi-national organizations such as the UN in forging the consensus needed to address global issues like climate change. Faced with these limitations, some countries are turning to the justice system. In another of our Top Stories, AP World News reported on a landmark case being heard about climate change at the International Court of Justice (ICJ), the top court of the UN based in The Hague, Netherlands. According to AP, the case is the largest ever taken up by the ICJ, with written comments from 62 nations and organizations. The case, which was sent by the court by the UN General Assembly, was brought by several small island nations hoping to hold major polluting nations to account. While any decision by the ICJ would be non-binding and would not directly force wealthy nations into action, AP notes that “it would be more than just a powerful symbol since it could be the basis for other legal actions, including domestic lawsuits.”

Our team at G&A is continuing to monitor developments around the world that impact efforts by governments and businesses to combat climate change. We look forward to keeping you updated and are available to provide guidance on how these developments could affect your sustainability goals and targets. Email us at info@ga-institute.com.

This is just the introduction of G&A’s Sustainability Highlights newsletter this week. Click here to view the full issue.

Originally published on Illumina News Center

Illumina recently launched the MiSeq i100 and MiSeq i100 Plus Systems, two powerful, compact benchtop sequencers that incorporate more than 140 invention disclosures and 60 patent families. On our News Center, we are celebrating outstanding employees who helped develop this breakthrough technology.

“If you’re a kid who likes science, you sort of assume that your pick of profession is either a veterinarian, doctor, or astronaut,” says Illumina Associate Director of Scientific Research Erin Imsand. “No one tells you you can make technology that makes a difference in the world.”

In her academic and professional careers, Imsand has immersed herself in several different scientific disciplines—and this cross-functional experience has served her well. In fact, it may be her secret sauce.

She earned her bachelor’s in chemical engineering and researched green energy in a project commissioned by Hyundai. She received a PhD in biochemistry—having never taken an undergraduate course in the subject. She ran a yeast biochemistry team making biofuels for BP before she realized that clean energy was moving toward electric vehicles. “It became pretty clear that I was not going to see the launch of anything I was working on,” she says, “and that really matters to me.”

At the time, Imsand had friends working at Illumina who said they “definitely launched products.” She remembers thinking that launching products would fill her soul a little more. Imsand joined Illumina seven years ago in what was then called Life Cycle Management.

With a background in engineering and basic sciences, she fit nicely in Operations, in between the development scientists and the manufacturing team. She started working on some of Illumina’s oncology products, such as TruSight Oncology 500.

After about a year and a half, Imsand was approached about a project still in the concept stage—what would become the NovaSeq X. She was asked to help incorporate lyophilization (better known as “freeze drying”) into the product’s sequencing reagents, which had previously required dry ice shipping and cold storage. If they could pull it off, the process could stabilize reagent biomolecules, raising the temperature at which they could be shipped. Through a lot of hard work, Imsand and a team of scientists were able to map out a way to design the first Illumina product to use lyophilization—and ambient shipping.

But lyophilization of sequencing reagents could be pushed further—in addition to shipping, what if the reagents could be stored at room temperature? Imsand, having now moved to R&D, got the chance to experiment when she was asked to run the entire reagent team for the new MiSeq i100 project.

“Liquid is like a mosh pit for biomolecules,” she says. “They can jump around and crash into each other, and that mobility can drive the shelf life and thermal stability really, really low. That’s why we tend to freeze our reagents.” However, she explains, freezing only minimizes molecular mobility—it doesn’t stop it completely. Ice crystals can actually move in the frozen solid. Lyophilization uses a partial vacuum chamber to reduce the atmospheric pressure on a frozen material to the point where its water ice can transition directly from solid to gas, a process called sublimation. This removes nearly all the water content from the materialthe same way food is freeze dried. What remains is a dry powder or cake (like with NovaSeq X) or, in the case of the MiSeq i100, microspheres. A cartridge is filled with these solid little dry balls, which are later rehydrated on the instrument.

Lyophilization enables these new reagents to last far longer than previous versions, and the cartridges don’t need to thaw before use. “I think customers are really, really going to love being able to store the reagents on the benchtop,” Imsand says. “No more refrigerator space required. No more freezer space required.”

In addition to the microspheres, her team also developed the enzymes, fully functionalized nucleotides, and other materials that go into the reagents. Depending on the current phase of whichever program they’re working on, their activities range quite widely, from developing analytical methods, raw materials, or formulations, to establishing the processes to make them. Over the course of three years, she has worked closely with a number of teams, including the flow cell team (her reagents work on the flow cell), the cartridge team (who fill the cartridges with microspheres) and the operations team, whom they collaborated with to transfer the microsphere-making technology into a robust manufacturing process that’s continuously reproducible.

An evolving field and industry

What does it take to work with someone like Erin Imsand? “With our movement into lyophilization, we have graduated into a brave new world where you have to be a little bit equipment engineer, a little bit process engineer, a lot chemist,” she says. An ideal candidate is “someone who’s fearless, because there’s not a ton of industry precedent for what we’re doing.” The ideal candidate can also integrate multiple requirements into one system. “A lyophilized reagent, for example, has to be moisture tolerant; it can’t be super staticky or super foamy. You have to be able to think outside the box and not get too discouraged by hard problems.” Imsand adds that a person could have a PhD or not, a background in manufacturing, basic chemistry, engineering, or another area, and still be very successful on her team. “What’s nice is there’s almost no way you could come in with all the experience needed. You have to learn on the job.”

On the heels of launching two products that use lyophilization, Imsand envisions an exciting and innovative future for the genomics industry, and one that welcomes all kinds of talent. “We were the first company to do clustering chemistry on the sequencer—you used to have to buy two different instruments, one to do clustering, one to do the actual sequencing,” she says. “We made a patterned flow cell using a more cost-efficient manufacturing process to help drive sequencing costs down. We’ve had these big step changes in the industry driven by Illumina. I think lyophilization is going to be one of these next really big steps and I can’t wait to recognize my team. They were part of this, they did it, they pioneered it, and now we’ve just set a precedent that others will be following for the next decade.”

Originally published on GoDaddy LinkedIn

Welcome to the latest issue of the GoDaddy Venture Forward newsletter! Here we share our latest exclusive data, insights and news about small and microbusinesses.

Venture Forward is a GoDaddy research initiative started in 2018 to quantify the growth and impact of online microbusinesses on their local economies, and to provide a unique view into the attitudes, demographics and needs of these entrepreneurs. To date, Venture Forward has surveyed more than 50,000 entrepreneurs with a digital presence, making it the source for microbusiness data and insights. GoDaddy defines microbusinesses as small businesses with a unique domain, an active website and most often fewer than 10 employees.

If you haven’t already, subscribe to this newsletter to get updates in your LinkedIn feed each quarter!

Alexandra Rosen
Global Head, Venture Forward

Updated Microbusiness Data Hub

We refreshed the Venture Forward Microbusiness Data Hub through September 2024 across Australia, Canada, U.K. and U.S., including updated microbusiness density data, U.S. Microbusiness Activity Index and global e-commerce trends.

Here are two sets of rankings – the first by sector of the economy and the second by Microbusiness Density across geographies – for the U.S., U.K., Canada and Australia:

Top five e-commerce industries (based on order count) in each country:COUNTRYTOP2ND3RD4TH5THU.S.BeautyHealth/MedicalRetailFitness/WellnessFashionU.K.BeautyPetsHealth/MedicalFitness/WellnessRetailCanadaBeautyHealth/MedicalFitness/WellnessSportsAutoAustraliaHealth/MedicalBeautyFitness/WellnessEducationPetsSource: GoDaddy Venture Forward, Q2 2024Top five areas ranked by Microbusiness Density (the number of microbusinesses per 100 people) in each country:COUNTRYTOP2ND3RD4TH5THAustralia (SA3)Adelade CitySydney Inner CityMelbourne CityNorth Sydney – MosmanEastern Suburbs – NorthMicrobusiness Density66554Canada (Province)British ColumbiaOntarioAlbertaQuebecYukonMicrobusiness Density32221U.K. (Constituency)Cities of London and WestminsterStoke-on-Trent SouthSt AlbansHolborn and St PancrasHackney South and ShoreditchMicrobusiness Density2314998U.S. (Lg. Metros: pop. 400K+)New York, NYTulsa, OKLas Vegas, NVFt. Lauderdale, FLMiami, FLMicrobusiness Density2927202019      Source: GoDaddy Venture Forward, Q2 2024    

Download the data

GoDaddy Venture Forward Annual 2024 Report + New Interactive Landing Page

Venture Forward released its 2024 annual report across Australia, Canada, the United Kingdom and the United States with a new interactive landing page, including an customizable map with microbusiness data points over time on digital businesses with typically fewer than 10 employees. We invite you to explore and download the full report for extended insights and an exclusive dive into what’s happening with online entrepreneurs in 2024.

Top 10 States By Microbusiness Count GrowthSTATE1 year Microbusiness Count % Growth5 year Microbusiness Count % GrowthActive Microbusinesses July/Aug ’24Microbusiness Density July/Aug ’24Delaware65%359%381,54338.4Montana45%61%83,1327.6Nevada36%44%601,05819.4Washington31%50%720,8369.4Colorado24%30%598,24910.4New York21%29%1,832,2989.2California14%19%4,026,19710.2Florida14%32%2,471,41211.4Oklahoma14%57%289,6667.3Wyoming14%212%112,42119.5

2024 report highlights

Three-quarters of U.S. microbusiness owners relaunch after setbacks

75% of microbusiness owners who close a business don’t give up, even if their efforts didn’t yield a profit. Instead, they persist, launching new ventures. Of these, 39% become the main income for their households.

Microbusiness owners are placing greater confidence in themselves. They are less swayed by uncertainty in the economy. Only 39% say they are confident in the national economy. But 74% are optimistic about their business prospects in the next six months. Even among those pessimistic about the economy, one in four plans to hire within a year. Entrepreneurs are making decisions based on business needs rather than on the economy.

AI driving job creation in the United Kingdom

While some narratives suggest that AI may lead to the loss of jobs, GoDaddy’s data suggests that among microbusinesses it is quite the opposite. Entrepreneurs are using the technology to automate time-intensive jobs such as copy-writing (70%), summarizing information (51%) and content creation (40%), which is allowing many to focus on expansion.

Microbusinesses using AI are twice as likely to employ at least one other person than those that do not, while nearly half (47%) of employees are at AI-supported businesses work full time, compared to 34% of employees at non-AI businesses.

Meanwhile, in the next twelve months, more a third (36%) of entrepreneurs using AI plan to hire more staff, compared to one in six (15%) who are not. They were also three times as likely anticipate “substantial” workforce expansion in the coming year.

Other Key Findings

Also revealed in the GoDaddy Venture Forward 2024 US Report: “In 2021, we first revealed the outsized economic impact made by microbusinesses. Together with economists and academic researchers, we uncovered that they drove up jobs and annual household median incomes, and drove down unemployment. Specifically, the job impact has grown from two or more jobs created for every microbusiness in 2020, to over seven jobs for every microbusiness entrepreneur on a county-level.”

Economic Contribution: Microbusinesses, defined as businesses with fewer than ten employees, contribute to 7 jobs at the county level.Entrepreneurial Resilience: 75% of microbusiness owners demonstrate exceptional perseverance by relaunching their ventures after setbacks, showing their adaptability and commitment despite challenges.Technology Adoption: Entrepreneurs are increasingly leveraging digital tools and platforms, with significant use cases in e-commerce, marketing, and operational management, driving efficiency and competitiveness.Community Impact: Microbusinesses are vital to strengthening communities, creating opportunities, and fostering a sense of connection through hyper-localized operations.Growth Drivers: Small business owners identify personalized customer engagement, digital marketing, and innovative service offerings as key strategies for sustained growth in 2024.Migration Impact: Areas that saw more people move into their counties, also saw a greater increase in the density of microbusinesses. The farther the move, the greater the impact.

Read the full report

In The News

US

Microbusiness Owners’ Top Business Challenges and Opportunities Identified by GoDaddy Data – Small Business Currents

GoDaddy data points to high entrepreneurial activity across US states and cities, signalling opportunities to tailor products locally. A GoDaddy survey identified top challenges for microbusiness owners are marketing, accounting and healthcare, revealing areas for tailored solutions.

Read more in Small Business Currents

U.K.

The top five ways AI could help level the playing field for microbusinesses – Elite Business

GoDaddy surveyed UK small business owners and found 58% want the government to fund technology adoption, indicating a desire for tech subsidies. GoDaddy research suggests AI tools could significantly help microbusinesses compete by improving accounting, inventory and other tasks.

Read more here

Australia

Australian entrepreneurs thrive without degrees, GoDaddy finds – IT Brief

GoDaddy research found two-thirds of Australian entrepreneurs are succeeding without college degrees, showing opportunities to support non-traditional founders. Over 1.4 million Australians now have side hustles according to a study, pointing to a growing microbusiness economy especially since the pandemic.

Read more in IT Brief

Canada

Gen Z Entrepreneurs Ditching University In Favour Of Starting Their Own Businesses – Muskoka411

A GoDaddy study revealed 61% of Gen Z Canadians are skipping college to start their own businesses, highlighting motivated young entrepreneurs needing support. GoDaddy data shows microbusinesses are struggling to implement new technologies like AI, underscoring difficulties smaller companies face with digital adoption.

Read more in Muskoka411 here

Logitech Blog

Authored by Marie Perriard, Sustainability Marketing & Communications 

New to buying used? Finding hidden gems in a secondhand market can feel like you’ve hit the jackpot. The mix of satisfaction from finding the perfect item lower than its original price provides that sense of accomplishment. Logitech is making it easier to find top-notch refurbished devices online. In addition to refreshing both Logitech.com and LogitechG.com online shopping portals with more refurbished products, it recently unveiled its Certified Refurbished devices on eBay’s Refurbished brand store.

What Are Certified Refurbished Electronics?

Gone are the days of disposable tech. Today’s discerning shoppers see electronics as long-term investments. Refurbished devices are pre-owned devices returned to the manufacturer or retailer for various reasons. The devices are thoroughly tested, repaired if necessary, and restored to like-new condition. They undergo rigorous quality checks to ensure they meet high standards of performance and reliability.

Why Go Refurbished?

Cost-Effective: One of the biggest perks of buying refurbished devices is the price. Buying secondhand items or open-box returns from retailers can be a fraction of the price of new items, including name brand items. Whether it’s a top-tier gaming device, a high-end keyboard, or multi-function mouse, refurbished devices offer incredible value.Environmental Impact: Buying refurbished electronics reduces electronic waste and the environmental impact of manufacturing new devices. In the current age of climate consciousness, sustainability matters more than ever.Quality Assurance: No need to worry about quality. Reputable brands and retailers ensure that refurbished devices are thoroughly tested and meet stringent quality standards. Logitech Certified Refurbished devices are inspected by a third party and include the required accessories and manuals provided with new products, all fully restored and ready to deliver an exceptional experience. Plus, they have a warranty from the date of purchase.Longevity and Durability: People are moving away from the ‘throwaway’ culture and looking for products that last longer. Logitech Certified Refurbished devices undergo rigorous testing and repairs, making them just as durable and reliable as new ones.

Tips for Buying Refurbished Electronics

Buy from Reputable Sellers: Ensure you’re purchasing from reputable brands or certified e-tail and retailers. Look for warranties and return policies to protect your investment. Logitech and Logitech G sell Certified Refurbished devices directly online and through the eBay Refurbished Logitech brand store.Check for Certification: Certified refurbished products often come with a seal of approval or certification, indicating the devices have been tested and restored to meet specific standards. Before returning a product to the marketplace, a third party inspects Logitech products.Read Reviews: Customer reviews can provide valuable insight into the quality and reliability of refurbished products from particular sellers.

The rise of refurbished electronics is a testament to how consumer habits are evolving. People are becoming more mindful of their environmental footprints and looking for smarter, more sustainable ways to enjoy the technology we love. The next time you are considering a new device, why not give refurbished a try? It’s a savvy, sustainable choice that won’t break the bank – and you might find that buying secondhand feels more like first class.

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