DP World is proud to support one of the largest global shipments of electric buses, advancing Chile’s national commitment to sustainable urban transport. Our terminal in San Antonio has successfully received the first 300 electric buses from China – part of a total 1,800-bus fleet destined for Santiago, the nation’s capital.

This landmark initiative will help Santiago reach its goal of converting 68% of its public bus fleet to electric, significantly reducing emissions and enhancing mobility for more than 3.5 million residents. The shipment marks a major milestone in global clean energy logistics, connecting Chile to a more sustainable future.

“We are pleased to have ensured the safe and timely arrival of this first batch of electric buses at our terminal in San Antonio,” said Stephenie Dewulf, Commercial Manager at DP World San Antonio. “Without a doubt, these will have a positive impact on many people, and we are proud to play such a key role in Chile’s automotive supply chain, leading the logistical efforts to see these buses reach their final destination as planned.”

With over 90% of vehicle imports to Chile passing through DP World’s San Antonio terminal, our dedicated team and specialized facilities ensure safe, efficient handling of electric buses to their final destinations.

Chile’s Minister of Transport, Juan Carlos Muñoz, commented: “This is very good news for our public transportation system. This consolidates our country’s leadership in the use of this type of technology, since by the end of the year, three out of every five buses circulating in Santiago will be electric.”

The new fleet will add to the 2,555 electric buses already on Santiago’s streets, bringing the total to more than 4,300. Each vehicle includes upgraded safety and accessibility features such as blind spot sensors, Wi-Fi, USB chargers, air conditioning, and security cameras – enhancing both passenger experience and road safety.

DP World remains committed to unlocking opportunities and driving sustainable growth. As the remaining electric buses arrive in the coming months, our San Antonio terminal stands ready to support Chile’s bold transition to cleaner, smarter transportation.

WILMINGTON, Del., May 20, 2025 /3BL/ – The Chemours Company (Chemours) (NYSE: CC), a global chemistry company, announced a strategic agreement with DataVolt, a designer, developer, and operator of sustainable digital infrastructure, to further demonstrate and develop advanced liquid cooling solutions for data centers alongside other industry leaders. This collaboration will focus on increasing data center efficiency and sustainability through two-phase direct-to-chip, two-phase immersion cooling, and other innovative solutions. The companies will work to enhance infrastructure readiness and address the increasing demands of artificial intelligence (AI) and next-generation chips.

“Our collaboration with DataVolt represents another significant step in our liquid cooling roadmap,” said Denise Dignam, Chemours President and CEO. “Combining our thermal management expertise with DataVolt’s knowledge designing and operating sustainable data centers, we can help accelerate the adoption of liquid cooling and other innovative technologies, minimizing data center total cost of ownership and environmental footprint, while maximizing performance and efficiency. We are excited to work alongside industry leaders to achieve these goals and drive forward sustainable data center innovation.”

The agreement includes the development of liquid cooling and other data center solutions using Chemours’ portfolio of ultra-low global warming potential Opteon™ dielectric fluids. This is the latest announcement from Chemours Liquid Cooling portfolio, which aims to provide a comprehensive portfolio of data center cooling solutions to support AI and advanced digital infrastructure.

“We are excited to announce this agreement with Chemours to develop state-of-the-art solutions—including liquid cooling technologies–for our future-ready AI data centers,” said Rajit Nanda, DataVolt CEO. “This collaboration underscores our commitment to be at the forefront of innovation as we serve the world’s insatiable need for eco-friendly, high-performance and mission critical AI factories that can support ever increasing compute densities while also being rapidly deployable, sustainable and cost effective. By integrating Chemours’ advanced liquid cooling solutions and engaging partners from across the industry, we aim to enhance the efficiency and scalability of our data centers, ensuring they meet the rapidly evolving demands of next-generation AI applications.”

As data center demands continue to rise, liquid cooling technology—such as Chemours’ Opteon™ two-phase immersion cooling fluid— offers significant benefits, including up to 90% cooling energy reduction, up to 40% reduction in total cost of ownership, nearly eliminating water use, and enabling increased computing capacity and density per square foot without compromising performance. Additionally, Chemours liquid cooling solutions support circularity—enabling heat and some fluids to be recovered and reused to drive further efficiency and sustainability benefits.

For more information, visit Opteon.com.

About The Chemours Company
The Chemours Company (NYSE: CC) is a global leader in providing industrial and specialty chemicals products for markets, including coatings, plastics, refrigeration and air conditioning, transportation, semiconductor and advanced electronics, general industrial, and oil and gas. Through our three businesses –Thermal & Specialized Solutions, Titanium Technologies, and Advanced Performance Materials – we deliver application expertise and chemistry-based innovations that solve customers’ biggest challenges. Our flagship products are sold under prominent brands such as Opteon™, Freon™, Ti-Pure™, Nafion™, Teflon™, Viton™, and Krytox™. Headquartered in Wilmington, Delaware and listed on the NYSE under the symbol CC, Chemours has approximately 6,000 employees and 28 manufacturing sites and serves approximately 2,500 customers in approximately 110 countries. For more information, visit chemours.com or follow us on LinkedIn.

About DataVolt
DataVolt is designer, developer, and operator of sustainable digital infrastructure, integrating dedicated high-availability multi-technology renewable energy infrastructure solutions and green fuels, with a strong focus on innovation, sustainability, and scalability. Headquartered in Saudi Arabia, with offices currently in the USA, Uzbekistan, India, and the UAE, and presence in South Korea and South Africa. DataVolt has strong global ambitions spanning across the Middle East, Africa, and Asia. DataVolt’s core focus is servicing the needs of hyperscalers, large enterprises, and government institutions. www.data-volt.com

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CAMBRIDGE, Mass.–(BUSINESS WIRE)–Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today the publication of its 2024 Corporate Responsibility Report. Guided by the theme of “Accepting Challenges to Improve the Health of Humanity,” Alnylam continues to take meaningful steps across each of its six corporate responsibility pillars. This year’s edition highlights the company’s progress, data, and stories demonstrating its commitment to patient access,

SAN FRANCISCO–(BUSINESS WIRE)–Cool Effect, a Bay Area nonprofit that supports high integrity carbon emission reduction and removal projects around the globe, is announcing today that it has selected a Direct Air Capture (DAC) project to be added to its portfolio of carbon projects. After a comprehensive review, Cool Effect has chosen to represent Project Juniper, a DAC project in Nevada owned and operated by LA-based project developer Clairity Technology. This marks the first time that Cool E

  • Applications for funding will be accepted through June 30 for eligible nonprofit organizations

CHARLOTTE, N.C., May 20, 2025 /3BL/ – Duke Energy Foundation announced a commitment of $500,000 in new funding designed to support local environmental impact programs across North Carolina.

How it works: Eligible organizations can now apply for grants of up to $25,000. Applications are live on Duke Energy Foundation’s website and will remain open until Monday, June 30, at 5 p.m. 

The impact: The funding will support programs focused on improving natural environments, enhancing community resilience, promoting land conservation, advancing clean water initiatives and supporting biodiversity.

“We are proud to support initiatives that enhance our natural surroundings and bolster community resilience,” said Kendal Bowman, Duke Energy’s North Carolina president. “Our goal is to contribute to the well-being of the communities we serve by partnering with organizations which recognize that North Carolina’s natural environment is one of our most important assets.”

Looking back: During the past two years, the Foundation has provided funding to more than 50 environmental impact initiatives in North Carolina. Examples of recent collaborations include coastal restoration work, wildlife habitat rehabilitation and local environmental science educational programs.

Duke Energy Foundation

Duke Energy Foundation provides more than $30 million annually in philanthropic support to meet the needs of communities where Duke Energy customers live and work. The Foundation is funded by Duke Energy shareholders.

Duke Energy

Duke Energy (NYSE: DUK), a Fortune 150 company headquartered in Charlotte, N.C., is one of America’s largest energy holding companies. The company’s electric utilities serve 8.6 million customers in North Carolina, South Carolina, Florida, Indiana, Ohio and Kentucky, and collectively own 55,100 megawatts of energy capacity. Its natural gas utilities serve 1.7 million customers in North Carolina, South Carolina, Tennessee, Ohio and Kentucky.

Duke Energy is executing an ambitious energy transition, keeping customer reliability and value at the forefront as it builds a smarter energy future. The company is investing in major electric grid upgrades and cleaner generation, including natural gas, nuclear, renewables and energy storage.

More information is available at duke-energy.com and the Duke Energy News Center. Follow Duke Energy on XLinkedInInstagram and Facebook, and visit illumination for stories about the people and innovations powering our energy transition.

Contact: Garrett Poorman
24-Hour: 800.559.3853
Twitter: @DukeEnergyNC

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Cisco’s Purpose to Power an Inclusive Future for All isn’t a standalone initiative – it’s embedded and operationalized throughout our company and drives growth for our business, people, and communities.

That’s why you’ll see Purpose front and center at Cisco Live San Diego from June 9-12, 2025 – our biggest global customer event that brings together top experts, partners, and customers to experience our innovations firsthand.

We’re celebrating 40 years of impact in our Purpose Pavilion and showing how we put our Purpose into practice. From theater sessions to demos, here’s what’s in store:

Purpose Pavilion Theater 

The Purpose Pavilion is located in the World of Solutions, where onsite attendees will discover cutting-edge technology, get a glimpse into future innovations, and network with experts and peers.

Our Purpose Pavilion Theater will feature leaders in sustainability, digital impact, social impact, public policy, and AI, sharing business solutions and industry insights. Register for the sessions so you don’t miss out, and don’t worry – these sessions will also be available on-demand a few weeks after the event. Here’s a sampling of the sessions you can expect to see:

  • AI Policy: Global Implications and Regulatory Shifts
    Speaker: Jeff Campbell, SVP and Chief Government Strategy Officer, Cisco
    As AI continues to transform industries and societies, governments are weighing how to balance innovation with oversight, and the U.S. stance could set the tone for regulatory approaches in other regions. In this session, you’ll gain insight into how U.S. decisions may shape global AI regulation and Cisco’s role in guiding the future of AI policy.
  • Offices that Everyone Loves: Smart Tech for Inclusive Spaces
    Speakers: Brian Tippens, SVP, Social Impact & Inclusion, Cisco; Christian Bigsby, SVP, Workplace Resources, Cisco; Stephen Brown, SVP Global Market Development, International Well Building Institute
    Wondering how to make your office a place where everyone feels welcome and productive? Join Cisco’s experts in real estate and social impact & inclusion to see how Cisco blends cutting-edge tech with design to meet the needs of today’s workforce. We’ll share real-life examples of Cisco offices, demonstrating how to create spaces that spark innovation and collaboration while being mindful of accessibility, personal preferences, and wellbeing.
  • Digital Resiliency Unlocked: Power Sustainable, Secure, and Inclusive Communities
    Speakers: Guy Diedrich, SVP and Global Innovation Officer, Cisco; John Paul Morgan, CTO of Morgan Solar; Dr. Xiang Liu, Ph.D. Director of Rutgers Rail & Transit Program at Rutgers University
    Celebrate a decade of digital transformation with the Country Digital Acceleration (CDA) program, which powers sustainable, secure, and inclusive communities. Discover how Cisco’s AI-driven technologies can enhance your operational efficiency and security, revolutionize public transportation systems globally, and bridge the digital skills gap.
  • Circular Design Can Increase Efficiency and Cut Costs
    Speakers: Mary de Wysocki, SVP and Chief Sustainability Officer, Cisco; David Stallings, VP of Hardware Engineering, Cisco
    Many IT leaders are tasked with reducing their network’s impact on the environment, all while keeping costs down, maintaining performance, and supporting increased workloads. Cisco is helping you address this challenge through its Circular Design Principles – which can help you keep your hardware in service longer, lower your energy use, reduce e-waste, and even cut costs. Hear from a product engineering leader who is incorporating circular design into the products you use, and see examples of products that can help you address both business- and sustainability benefits to your company.

Sustainability

We strive to reduce Cisco’s environmental footprint and to use our technology and expertise to help our customers and suppliers reduce theirs. Check out our sustainability demo in the Purpose Pavilion, where we’ll show how we extend product life through circular programs like product takeback, remanufacture, and reuse.

And, behind the scenes: here are just some of the ways we’re reducing our carbon footprint across the event, increasing our landfill diversion rate, and decreasing total waste per person onsite:

  • We don’t serve plastic water bottles at the event – instead, we encourage attendees to bring their own reusable water bottles and use our onsite water stations. This strategy helped eliminate the use of an estimated 71,000 PET plastic water bottles at Cisco Live ’24*.
  • We leverage rental inventory. An estimated 500,000 pounds of furniture, furnishings, and kiosks were saved for reuse from Cisco Live ‘24*.
  • We work closely with our venues to donate unserved food. At our Celebration at Cisco Live ’24, we donated almost 7,000 meals to those in need in the community*.

* This data is based on calculations by MeetGreen and is provided for informational purposes only.

Demos

We’ve built the digital highways that have become the backbone for modern communication. Now, we’re harnessing the power of connection to build a better future for people, communities, and the planet, and Cisco Live attendees can get hands-on with our latest technology at onsite demos at the Purpose Pavilion.

We’re also bringing the impressive Cisco Crisis Response Network Emergency Responsible Vehicle (NERV) to show how we support on-the-ground connectivity during humanitarian crises and natural disasters – an essential need when people need access to digital cash, relief benefits, social services, communication with loved ones, and more.

Health and Well-being

Cisco Live is a jam-packed four days, so stop by the Powered by Purpose café for coffee, juice, and seating space to relax and reenergize.

Powering Purpose Beyond Cisco Live

Our Purpose goes hand-in-hand with our business strategy, so take advantage of all the ways to get involved at Cisco Live and beyond. Check out the progress we’ve made to combine our technology, people, and broader networks in our latest FY24 Purpose Report.

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MIAMI, May 20, 2025 /PRNewswire/ — CommunityRewards™ powered by Points4Purpose, Inc. is pleased to announce its new charity partnership with the Juanfe Foundation, a Colombian-based charity dedicated to empowering young Latina women and moms throughout South America through educational, mental health and job training programs.

Through this strategic partnership, CommunityRewards™ is hosting a fundraiser on its loyalty rewards platform as one of its featured charity organizations so that shoppers can micro-donate a portion of their cashback rewards to the organization and support its on-going efforts to help impoverished women and children in need throughout South America.

As a growing AI-powered loyalty rewards and micro-donation platform that helps businesses enhance their bottom line through charitable giving and rewards marketing solutions, CommunityRewards leadership team is proud to support women in need. “As so many charities across the U.S. and South America continue to see the federal government cut funding, we’re working towards bridging the gap and providing charities a new source of micro-funding,” said James Trocme, Chief Operating Officer of Points4Purpose, Inc.

CommunityRewards™ is on a mission to transform everyday spending into opportunities for both personal fulfillment and charitable giving powered by encrypted, card-linking technology, generative AI and big data. “This is a first-of-its-kind rewards platform that infuses micro-charitable donations into regular, everyday financial transactions. We hope through this new partnership with Juanfe, the Latin community in Miami with family and friends living in Colombia will take advantage of our free platform to earn cashback and give back to charities like Juanfe that are supporting women and children get out of poverty with job training programs,” Trocme continued.

The CommunityRewards™ platform is designed to make it easy for businesses, charities and shoppers alike to join and participate without any IT integration, which is often required with other software solutions. “We’ve kept it simple with the CommunityRewards platform–Members can join for free, connect their preferred Visa, MasterCard or American Express card to their CommunityRewards™ Member ID, select their preferred charity and the percentage of cashback they wish to donate, and then begin simultaneously earning cashback on qualifying purchases while supporting a great charity like Juanfe,” Trocme said.

Juanfe was founded by Catalina Escobar after tragically losing her one and a half year old son. Following his untimely passing, Escobar made it her mission to solve the infant mortality epidemic in Colombia that so many Latina women were battling. “When I first founded Juanfe, with as little as $100, we were able to provide essential medical care and treatments to impoverished young mothers in Colombia and significantly reduce newborn mortality,” Escobar said. Fast forward to 2025, after drastically reducing the infant mortality rate, Juanfe has expanded its programs and services to help teenage mothers living in extreme poverty. “This is one of Colombia’s and Latin America’s biggest socioeconomic problems–teen pregnancy. We’ve developed new mental health counseling and jobs programs to empower young teen moms with information and respectable jobs that will allow them to support their families. Most recently, we just added a new program within our charity that actively addresses the sex trafficking and sexual abuse crisis affecting so many young, impressionable and impoverished Latina teenage girls in high school,” Escobar said.

Juanfe recently expanded its services and programs beyond Colombia to help young Venezuela girls escape the sex work, human trafficking and drug dealing industries by providing technical job training and job placement support, ultimately enabling them to enter the traditional job market and do a job they enjoy with dignity and pride. “We’re ecstatic to partner with CommunityRewards to help raise awareness about the adversities that young impoverished girls throughout South America are experiencing. We’re also grateful for the micro-fundraising being done on the CommunityRewards™ platform,” Escobar continued.

Miami businesses and shoppers alike can join CommunityRewards™ online at Miami.CommunityRewards.Store and begin earning cashback and supporting impactful charities like the Juanfe Foundation.

ABOUT COMMUNITYREWARDS™
CommunityRewards™ is powered by Points4Purpose, Inc. and is a seamless, card-linked loyalty rewards platform enabling consumers to seamlessly earn cashback on in-store and online purchases from more than 7,000 top participating retailers while donating a portion of their cashback earnings to the charity(s) of their choice. Learn more and join CommunityRewards online: https://miami.communityrewards.store. Follow CommunityRewards™ on Instagram @CommunityRewards.Store, Linkedin and Facebook for regular updates.

ABOUT POINTS4PURPOSE, INC.
Points4Purpose, Inc. is an innovative financial technology company based in Sydney, Australia with its North American headquarters based in New York City, providing loyalty rewards technology solutions throughout North America and Australia. Points4Purpose provides a unique, first-of-its-kind loyalty program that allows shoppers to earn cashback on purchases at qualifying retail partners with the option to donate a percentage to the charity of their choice. Ultimately, this revolutionary technology is leading the charge to make micro-philanthropy a part of everyday commerce transactions by connecting thousands of shoppers, brands and charity organizations together in one effortless platform. Through card-linking technology, Points4Purpose makes it seamless and easy for consumers to donate to local participating charities of their choice via their linked debit or credit card. To learn more Points4Purpose, please visit https://points4purpose.com.

ABOUT THE JUANFE FOUNDATION
Founded in 2001, the Juanfe Foundation is based in Colombia with the mission to improve the quality of life for young Latina teenage mothers and their children living in impoverished areas across Colombia and South America. Founded by Catalina Escobar who became an advocate and activist for women and children after experiencing a family tragedy, she has devoted her life to saving the lives of infants, young children and pregnant girls living in poverty throughout South America through vocational educational training and healthcare programs. Through the foundation’s 360 degree program spanning over two years and three phases, young women learn new social skills, receive self-esteem development, mental health support, job training and job recruitment placement as well as essential resources including daily meals, housing and healthcare. To date, more than 300,000 people in Colombia have been impacted by the Juanfe Foundation’s programs. To learn more or to support the Juanfe Foundation, please visit juanfe.org and https://www.instagram.com/fundacionjuanfe.

Contact:
Samantha Savory
3055825997
395496@email4pr.com

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/communityrewards-partners-with-the-juanfe-foundation-to-empower-and-fundraise-for-impoverished-teen-mothers-in-colombia-with-educational-and-job-training-programs-302460489.html

SOURCE Points4Purpose, Inc.

Congratulations to our very own Tomas Cihlar, Senior Vice President of Research, Virology, for being named to TIME’s list of the 100 Most Influential People in the World. His inclusion is an incredible honor and represents the work of hundreds of his Gilead colleagues and external partners, as well as nearly 20 years of groundbreaking HIV research and development. This is a significant acknowledgment of the progress in our work to end the epidemic for everyone, everywhere.

Gilead Sciences
Gilead Sciences, Inc. is a research-based biopharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. The company strives to transform and simplify care for people with life-threatening illnesses around the world. Gilead has operations in more than 35 countries worldwide, with headquarters in Foster City, California. 

Originally published by Gilead Sciences

MONTREAL, May 20, 2025 /3BL/ – Gildan Activewear Inc. (GIL: TSX and NYSE) (“Gildan” or “the Company”) is pleased to announce the publication of its 21st Environmental, Social, and Governance (ESG) Report, outlining the Company’s continued progress against the ten targets of its Next Generation ESG strategy.

“Over the years, ESG, which is one of three pillars of our Gildan Sustainable Growth (GSG) strategy, has been foundational to support our low-cost manufacturing operations, unlocking innovative business solutions and our ability to meet changing customer and consumer needs,” says Glenn Chamandy, President and CEO of Gildan. “Just as importantly, it has also helped us to attract and retain an engaged, experienced, and highly skilled workforce, and maintain the trust and support of the communities in which we operate. Together with our ~50,000 employees, we are committed to continue making apparel with respect.”

In 2024, Gildan achieved notable advancements towards its Next Generation ESG targets as the Company:

  • Reduced water intensity at its operated manufacturing facilities by 25.2% per kilogram produced (compared to a 2018 baseline) by leveraging innovative technologies and proprietary processes
  • Increased the amount of sustainable1 cotton sourced from 35.7% in 2023 to 77.3% in 2024
  • Doubled the percentage of recycled polyester or alternative fibre and/or yarns sourced from 2023 to 2024
  • Achieved ISO 45001 certification in two additional facilities in 2024, bringing the total number of certified facilities to five

Gildan also continued to be recognized for its ESG practices. The Company was:

  • Included on the Dow Jones Best-in-Class North America Index (formerly the Dow Jones Sustainability™ North America Index), marking the Company’s 12th consecutive year of inclusion in this index
  • Included in the 2025 Sustainability Yearbook by S&P Global for the 13th consecutive year
  • Included in CDP’s Leadership Band in 2025 for our 2024 climate change disclosure – marking the fifth time that Gildan has achieved this recognition
  • Named in the inaugural edition of TIME’s World Most Sustainable Companies
  • Recognized as one of Canada’s Best 50 Corporate Citizens by Corporate Knights for the third consecutive year

The full 2024 ESG Report and supporting indices and documents can be found here. To further enhance transparency and streamline reporting, we have included information about the Company’s approach to key ESG topics on our corporate website.

1. We consider the following types of cotton to be sustainable: sustainable cotton provided through third-party verified programs that support environmental and/or social sustainability improvements and/or outcomes. Sustainable cotton from third-party verified programs includes, for example, verified U.S.-grown cotton (USCTP), Better Cotton (formerly BCI), organic cotton, recycled or regenerative cotton, and fair-trade cotton.

About Gildan
Gildan is a leading manufacturer of everyday basic apparel. The Company’s product offering includes activewear, underwear and socks, sold to a broad range of customers, including wholesale distributors, screenprinters or embellishers, as well as to retailers that sell to consumers through their physical stores and/or e-commerce platforms and to global lifestyle brand companies. The Company markets its products in North America, Europe, Asia Pacific, and Latin America, under a diversified portfolio of Company-owned brands including Gildan®, American Apparel®, Comfort Colors®, GOLDTOE®, and Peds®, and under an exclusive licensing agreement for the printwear channel for Champion®.

Gildan owns and operates vertically integrated, large-scale manufacturing facilities which are primarily located in Central America, the Caribbean, North America, and Bangladesh. Gildan operates with a strong commitment to industry-leading labour, environmental and governance practices throughout its supply chain in accordance with its comprehensive ESG program embedded in the Company’s long-term business strategy. More information about the Company and its ESG practices and initiatives can be found at www.gildancorp.com.

Investor inquiries: 
Jessy Hayem, CFA 
Senior Vice-President, Head of Investor Relations and Global Communications 
(514) 744-8511 
jhayem@gildan.com

Media inquiries: 
Genevieve Gosselin 
Director, Global Communications and Corporate Marketing 
(514) 343-8814 
communications@gildan.com

Can complicated math equations help detect heart disease, even before you realize you’re sick? The answer appears to be yes, and they can do it by sifting through potential clues left behind during your trips to the doctor’s office.

“We now have the automated intelligence tools to help us collect and analyze mountains of medical data in ways that we couldn’t just a short time ago,” said Nina Goodheart, Senior Vice President and President of the Structural Heart and Aortic portfolio businesses at Medtronic. “Artificial intelligence (AI) allows us to examine that data to identify certain types of heart disease sooner and get personalized treatment to the patient faster.”

So what does that actually mean for you?

Let’s use the example of Aortic Stenosis (AS) — a serious heart problem that affects 250,000 Americans every year and often goes undertreated.

AS is a condition where the heart’s aortic valve gradually narrows and restricts blood flow from the heart to the rest of the body. When this happens the body sends out a variety of warning signals through symptoms that can be subtle, vary from person to person, and develop slowly over time. All of which makes diagnosing the problem difficult.

But whenever you visit the doctor, clues to your developing AS may be left behind. At every medical visit, lots of health information gets entered into your Electronic Health Record (EHR). It could include everything from your history of alcohol or tobacco use to vital signs to lab results to notes and observations from the doctor, and much more. The clues pointing to AS might be buried in that EHR data—but it can be a modern-day version of the needle in a haystack.

That’s where the math comes in.

“AI helps us bring order to what can sometimes be data chaos,” said Chris Rogers, Sr. Director of Strategic Provider Solutions at Tempus AI, a healthcare technology company based in Chicago that uses data and artificial intelligence to create medical diagnostic solutions. “Our algorithms can look for unique characteristics in the health data that a clinician might not identify for every one of their patients.”

The company’s software, known as Tempus Next, includes 60 highly complex algorithms, developed to identify potential care gaps across 15 cardiovascular diseases, including AS.

“Our software is designed to handle the complexity of medical data, which requires sophisticated and adaptable solutions,” Rogers explained. “There is no one-size-fits-all algorithm in healthcare. Each institution has unique needs and circumstances, and our technology is built to consider as much information as possible to provide tailored insights.”

Tempus Next combs through the data points in your EHR, even the handwritten notes from your doctor, and compares your information to the diagnostic criteria in clinical guidelines for AS. If your health information meets enough of the criteria, the system notifies your doctor for possible next steps.

It’s much more than a theoretical exercise.

Tempus recently finished a case study with the John Brancaccio St. Francis Hospital and Heart Center in New York. The Tempus Next algorithm identified 388 patients who met the criteria for AS and/or one other serious heart condition, but who did not yet have an existing plan to treat their disease. The Tempus Next system flagged their cases and alerted their doctors to the findings.

Math has made a potentially life-changing difference in each of their lives.

Now, Medtronic and Tempus are teaming up to take the next step—with a clinical study called ALERT—that will analyze health records at six more health sites. The objective is not only to identify patients who may be undertreated and get them to their next step in their care, but also to determine why that’s happening and help design systems to solve the issue.

“The under diagnosis of severe symptomatic aortic stenosis is a pervasive problem that can be fatal within two years without intervention. The goal of this study is to move towards better solutions for more equitable and timely care and to eliminate barriers to treatment,” said Wayne Batchelor, M.D., M.H.S., M.B.A., Interventional Cardiologist, President of the Medicine Service Line, Inova Health System, Fairfax, Va. and Steering Committee Chair of the ALERT study. The most exciting part, experts say, is the potential impact that such technology can have on human health.

“It’s breathtaking to think about the future,” Goodheart added. “Imagine the day when we can apply this technology to hundreds of thousands or millions of patients. Imagine the number of people we can reach before their AS becomes too severe. The number of lives we can lengthen or improve. It adds up in a hurry.”

That’s the kind of math everyone can appreciate.

This is one in a series of stories about how Medtronic is using math and AI to fight disease. Click here to learn how math can help prevent cancer.

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