MESA, Ariz.–(BUSINESS WIRE)–A new peer-reviewed study in mSystems, a journal of the American Society for Microbiology, finds that intestinal sulfide overproduction (ISO) is associated with a distinct gene-expression signature in the small bowel, one that looks markedly different from two related conditions commonly grouped with ISO.ISO, small intestinal bacterial overgrowth (SIBO), and intestinal methanogen overgrowth (IMO) are microbial imbalances closely tied to irritable bowel syndrome (IBS