Author: Ravi Shankar

CHENNAI, India, Oct. 21, 2026 (GLOBE NEWSWIRE) — Sify Technologies Limited (NASDAQ: SIFY), India’s leading Digital ICT solutions provider with global service capabilities spanning Data Center, Cloud, Networks, Security and Digital services, today announced that it will report its unaudited IFRS financial results for the Second quarter ended September 30, 2026 on Wednesday, October 28, 2026 before the market opens. 

In conjunction with the announcement, Sify will host a conference call at 8:30 AM ET with Mr. Raju Vegesna, Chairman of the Board and Mr. M P Vijay Kumar, Executive Director & Group CFO. Interested parties may participate by dialling +1-877-545-0320 (Toll Free in the U.S. or Canada) or +1-973-528-0002 (International), which will also be simultaneously broadcast live over the Internet at www.sifytechnologies.com/investors or https://www.webcaster4.com/Webcast/Page/2184/54697.

Please allow extra time prior to the call to visit the site and download the streaming media software required to listen to the Internet broadcast.

The online archive of the Webcast will be available shortly after the conference call. Investors can also listen to the replay by dialling +1-877-481-4010 (Toll Free in the U.S. or Canada) or +1-919-882-2331 (International) and entering the replay passcode 54697. Please allow for some time post conference call to access the archive of the Webcast. The replay is available until November 11, 2026.

About Sify Technologies

A multiple times Golden Peacock award winner for Corporate Governance, and with AI at the core of our solutions portfolio, Sify is focussed on the changing ICT requirements of the emerging digital landscape and the resultant demands from large, mid and small-sized businesses. 

Sify’s infrastructure comprising state-of-the-art data centers, the largest MPLS network, partnership with global technology majors and deep expertise in business transformation solutions modelled on the cloud, make it the first choice of large enterprises, start-ups and SMEs looking to scale.

Businesses across multiple verticals have taken advantage of our unassailable trinity of Data Centers, Networks and Security services and conduct their business seamlessly from across India. Internationally, Sify has presence across North America, the United Kingdom and Singapore.

Sify, Sify Technologies, Sify Infinit Spaces, www.sifytechnologies.com and www.sifyinfinitspaces.com are registered trademarks of Sify Technologies Limited.

Forward Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The forward-looking statements contained herein are subject to risks and uncertainties that could cause actual results to differ materially from those reflected in the forward-looking statements. Sify undertakes no duty to update any forward-looking statements.

For a discussion of the risks associated with Sify’s business, please see the discussion under the caption “Risk Factors” in the company’s Annual Report on Form 20-F for the year ended March 31, 2026, which has been filed with the United States Securities and Exchange Commission and is available by accessing the database maintained by the SEC at www.sec.gov, and Sify’s other reports filed with the SEC.

For further information, please contact:

Sify Technologies Limited Mr. Praveen Krishna Investor Relations & Public Relations +91 9840926523 praveen.krishna@sifycorp.com

20:20 Media Nikhila Kesavan +91 9840124036 nikhila.kesavan@2020msl.com

Luri Group Lucia Domville 646.824.2856 lucia.domville@lurigroup.com

Now live for eligible U.S. customers, with prediction markets business expected to contribute revenue beginning in Q4 2026

Commercial launch backed by established marketing and distribution partnerships to support customer acquisition and growth

LAS VEGAS, Nevada, Oct. 21, 2026 (GLOBE NEWSWIRE) — High Roller Technologies, Inc. (“High Roller” or the “Company”) (NYSE: ROLR), an online gaming and prediction markets company, today announced the commercial launch of ROLR^™, its real-money prediction markets platform, opening access to eligible U.S. customers following an invitation-only beta that began on September 15, 2026. With commercial operations underway, the Company expects its prediction markets business to begin contributing revenue in the fourth quarter of 2026.

“Today’s full commercial launch of our prediction markets platform is a defining milestone for High Roller as we bring ROLR to the public and begin the next phase of our growth,” said Seth Young, Chief Executive Officer of High Roller Technologies. “Our goal is to make prediction markets accessible and engaging through an intuitive customer experience, and our experience operating real-money consumer platforms provides a strong foundation for building this business.”

The launch marks High Roller’s entry into the U.S. prediction markets business, providing customers with access to event-based contracts offered by Crypto.com | Derivatives North America (“CDNA”). Through ROLR, eligible users can discover markets, trade contracts reflecting their views on real-world outcomes and manage their positions through a dedicated consumer platform.

Beta Testing and Launch Readiness

The September 15 closed beta was designed to assess the customer experience and operating infrastructure under controlled, live-platform conditions. Testing covered account registration, identity verification, geolocation, funding, market discovery, order entry, trading, position management, settlement, withdrawals and customer service.

“The commercial launch is the starting point for building lasting customer relationships and growing the ROLR platform,” added Young. “We are supporting the launch with a robust marketing plan designed to introduce ROLR to relevant audiences and convert that interest into active participation. Our priorities are to continually improve the product and execute a disciplined customer-acquisition strategy as we begin generating prediction markets revenue.”

Marketing and Customer Acquisition

High Roller’s commercial launch is supported by the Company’s previously announced marketing and distribution relationships, including Lines.com, Forever Network and Leverage Game Media. Together, management believes these relationships provide access to established digital audiences and multiple channels to build brand awareness and support customer acquisition.

Lines.com previously reported more than 100,000 indexed content pages and over 4 million social media followers, with content generating more than 500 million views in the 30 days preceding our April 2026 partnership announcement. Forever Network delivered more than 20 billion impressions in 2025, reaching 450 million people globally. Leverage Game Media has reported more than 1 billion annual views and over 5 million followers across its owned and operated channels.

SpikeUp Media will also support the launch through performance marketing and direct customer acquisition. Its track record includes more than 15 years of acquisition experience, driving over 1 million unique depositing customers to its partners, and more than $600 million in customer deposits. Additional marketing and distribution relationships further support the Company’s efforts to build awareness, reach new audiences and drive customer acquisition.

Established Technology and Operating Infrastructure

High Roller’s wholly owned subsidiary, ROLR US LLC, is a member of the National Futures Association and a registered guaranteed introducing broker operating under a guarantee agreement with OG Markets US, Inc., doing business as Crypto.com FCM. Customer accounts introduced through ROLR are carried by Crypto.com FCM; ROLR US LLC does not hold customer funds.

The platform incorporates technology provided through High Roller’s exclusive license and development agreement with mrkts.com, including a source code license and connectivity to Crypto.com services and CDNA, along with payments and compliance functionality. High Roller owns the customer-facing ROLR application, with the licensing framework providing flexibility to evolve the platform while retaining control over its customer experience and product roadmap.

ROLR is now available to eligible U.S. customers through desktop and mobile browsers, with dedicated iOS and Android apps planned to follow, subject to app store approvals. Eligible customers can access the platform at ROLR.com. Access and contract availability are subject to applicable eligibility requirements and geographic restrictions.

About High Roller Technologies, Inc.

High Roller Technologies, Inc. (NYSE: ROLR) is a publicly traded online gaming and prediction markets company, known for its innovative casino brands High Roller and Fruta, and its prediction markets brand, ROLR. The Company delivers cutting-edge real-money consumer facing products that are intuitive and user-friendly. With a diverse portfolio of over 6,000 premium online casino games from more than 90 leading game providers, High Roller Technologies offers an immersive and engaging gaming experience in the rapidly expanding multi-billion-dollar iGaming industry. As an award-winning operator, High Roller Technologies continues to redefine the future of market engagement through innovation, performance, and a commitment to excellence.

For more information, please visit the Company’s investor relations website and follow High Roller Technologies on X, Facebook, and LinkedIn.

Forward-Looking Statements

Certain statements in this press release constitute “forward-looking statements” within the meaning of the federal securities laws. Words such as “may,” “might,” “will,” “should,” “believe,” “expect,” “anticipate,” “estimate,” “continue,” “predict,” “forecast,” “project,” “plan,” “intend” or similar expressions, or statements regarding intent, belief, or current expectations, are forward-looking statements. Forward-looking statements are neither historical facts nor assurances of future performance. Instead, they are based only on our current beliefs, expectations and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy and other future conditions, the commercial launch and growth of the ROLR^™ prediction markets platform. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control. Our actual results and financial condition may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward-looking statements include, among others, our limited operating history in the prediction markets business; risks related to platform stability, scalability and technical performance, our ability to attract, convert and retain platform users and to generate revenue from the platform in the anticipated timeline or at all, the effectiveness of and cost of our marketing and customer-acquisition efforts and the performance of our marketing and distribution partners; our reliance on third parties, including Crypto.com | Derivatives North America, Crypto.com FCM and mrkts.com, and the continuation of our guarantee, license and development agreements; our ability to maintain the registration of ROLR US LLC as a guaranteed introducing broker and its membership in the National Futures Association, the evolving regulatory environment applicable to prediction markets and event-based contracts, and general market and economic conditions and such factors as discussed throughout Part I, Item 1A. Risk Factors and Part II, Item 7. Management’s Discussion and Analysis of Financial Condition and Results of Operations of our Annual Report on Form 10-K for the year ended December 31, 2025, Part I. Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations and Part II, Item 1A. Risk Factors, of our quarterly report on Form 10-Q for the quarter ended June 30, 2026 and in our other filings with the Securities and Exchange Commission. Any forward-looking statement made by us in this press release is based only on information currently available to us and speaks only as of the date on which it is made. We undertake no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.

Contact
Investor Relations
ir@highroller.com
800-460-1039

POINT ROBERTS, Wash., Oct. 21, 2026 (GLOBE NEWSWIRE) — Sanwire Corporation (“Sanwire” or the “Company”) (OTCID: SNWR), a diversified company with a focus on aggregating financial services and technologies, is pleased to announce that it has signed an agreement to acquire 100% of Bateau Asset Management Pty Ltd (“Bateau”), a boutique investment firm based in Australia with offices in Singapore. All figures are unaudited and reported in US dollars using an exchange rate of USD$1.00 equal to AUD$1.428 (Australian dollars).

Since its inception in 2016, Bateau has provided a consistent return on investment for its clients. Bateau’s current Global Opportunities Fund (the “Fund”) holds investments in Vanguard All-World ex-US Shares Index Exchange Traded Fund, Insync Global Capital Aware Fund, Apricor Capital, Impellor Small Companies Growth Fund, Hyperforge Fund and Supermaterials Fund. The Fund has a net asset value of over $7,500,000 (as of July 2026). To view the Fund’s performance reports, click here. Bateau has a well-established client base of high-net-worth individuals, serviced by Bateau’s experienced global client services team based in Australia and Singapore. The client services team also provides research and advisory services.

For the fiscal year ended June 30, 2025, Bateau reported revenues of $116,188. Bateau has since changed its fiscal year-end to December 31st, the same as Sanwire’s, and its 2026 fiscal year runs from January 1 to December 31, 2026. Commencing in Q4/2026, Sanwire will report Bateau’s financials on a consolidated basis. Sanwire will maintain a December 31st fiscal year-end for its annual disclosure filings and will report Bateau’s quarterly financials accordingly.

Under the terms of the acquisition agreement, Sanwire will acquire 100% of Bateau in exchange for the issuance of 1,424,115 shares of Sanwire’s Series G Preferred Stock convertible into common stock, a $250,000 convertible promissory note that matures on October 1, 2028 and is interest-free for the first 12 months, and a $100,000 cash payment payable in interest-free installments over a three-year period. Acquisition closing is anticipated in Q4/2026.

“We are delighted to be joining Sanwire,” said Wayne Blazejczyk of Bateau. “Since 2016 we have built this business around delivering consistent returns for our clients, and becoming part of a publicly traded group gives us the platform and resources to take it further. We believe this transaction will create long-term value for Sanwire’s shareholders, and our clients will continue to be looked after by the same team and the same investment approach.”

“In prior communications to our shareholders, we stated that we were looking for our next acquisition, preferably in the financial services market,” said Ron Hughes, President and CEO of Sanwire. “This acquisition will provide Sanwire with a new direction to build a solid foundation for future growth and acquisition opportunities. In addition, this acquisition provides Sanwire with an entry into the Australian and Southeast Asian financial services markets.”

About Bateau Asset Management Pty Ltd

Bateau is a boutique investment firm founded in 2016 and based in Australia with offices in Singapore. Bateau follows an absolute-return investment philosophy delivered by a multi-manager approach to investing. Services include investment research and education, with the objective of providing clients with rigorously constructed absolute-return portfolios that they can understand. To learn more, go to bateauam.com.au.

About Sanwire Corporation

Sanwire Corporation is a diversified company with a focus on aggregating financial services and technologies. For more information, visit sanwire.com.

For press and corporate inquiries, please contact:

Ronald E. Hughes
CEO, Sanwire Corporation
ron.hughes.management@gmail.com

Safe Harbor Statement

This release contains forward-looking statements. All statements regarding our expected future financial positions, results of operations, cash flows, financing plans, business strategy, products and services, competitive positions, growth opportunities, plans and objectives of management for future operations, listing on the OTC Markets, including words such as “anticipate,” “if,” “believe,” “plan,” “estimate,” “expect,” “intend,” “may,” “could,” “should,” “will,” and other similar expressions are forward-looking statements and involve risks, uncertainties, and contingencies, many of which are beyond our control, which may cause actual results, performance, or achievements to differ materially from anticipated results, performance, or achievements. We are under no obligation to (and expressly disclaim any such obligation to) update or alter our forward-looking statements, whether as a result of new information, future events, or otherwise.

Non-Binding MOU to Explore U.S.-Based Production, Assembly and Technical Support for HYTRON

Key Facts At-a-Glance

Who: Primech AI Pte. Ltd., a subsidiary of Primech Holdings Limited (Nasdaq: PMEC), and Sunnytech, an electronics contract manufacturer based in San Jose, California.

What: Signed a non-binding Memorandum of Understanding (MOU) to explore U.S.-based production and assembly of HYTRON, Primech AI’s autonomous restroom-cleaning robot, together with quality assurance, product testing and certification support for the U.S. market.

When: MOU signed October 20, 2026.

Where: San Jose, California, United States (Sunnytech) and Singapore (Primech AI).

Why It Matters: The MOU provides Primech AI with a potential pathway to U.S.-based production through Sunnytech, which could help shorten delivery lead times and support quality assurance closer to U.S. customers. The initiative aligns with Primech’s strategy to develop a scalable international robotics business.

How Much: The MOU is non-binding and does not commit either party to specific production volumes, manufacturing prices or other commercial terms, which would be subject to a definitive agreement.

SINGAPORE, Oct. 21, 2026 (GLOBE NEWSWIRE) — Primech Holdings Limited (Nasdaq: PMEC) (“Primech” or the “Company”), a Singapore-headquartered technology-driven facilities services and AI robotics group, today announced that its subsidiary, Primech AI Pte. Ltd. (“Primech AI”), signed a non-binding Memorandum of Understanding (“MOU”) with Sunnytech, an electronics contract manufacturer based in San Jose, California, on October 20, 2026, to explore U.S.-based production, assembly, quality assurance, testing and certification support for its flagship autonomous restroom-cleaning robot, HYTRON.

The MOU establishes a framework for both companies to evaluate potential production and technical support arrangements in the United States, supporting Primech AI’s ongoing efforts to expand HYTRON’s international commercial presence.

MOU Scope and Next Steps

Under the MOU, Sunnytech may undertake production and assembly of HYTRON based on Primech AI’s specifications, together with quality assurance, product testing and certification support. Both companies will evaluate these potential arrangements ahead of any definitive agreement. The timing and scale of any U.S. production have not been determined and would be subject to further discussions, applicable certification requirements and the execution of a definitive agreement.

Strategic Rationale for U.S. Production

The MOU builds on Primech AI’s ongoing efforts to expand HYTRON’s international presence, including its previous showcase at CES 2026 in Las Vegas.

Potential U.S.-based production could help shorten delivery lead times to customers in the region, while local quality assurance and product testing could support greater operational efficiency. Certification support under the MOU could also assist Primech AI in addressing applicable product safety requirements for the U.S. market.

Through the MOU, Primech AI and Sunnytech will evaluate how local production and technical support capabilities could contribute to HYTRON’s future commercialisation in the United States.

The proposed collaboration supports Primech AI’s broader strategy to strengthen HYTRON’s commercial presence in the U.S. market and develop a scalable international robotics business.

HYTRON Product Overview

HYTRON is a fully autonomous AI-powered restroom-cleaning robot designed to clean toilets, urinals, wash basins, sinks, mirrors and surrounding floor areas. Combining intelligent navigation with robotic manipulation, HYTRON automates repetitive cleaning tasks to support consistent hygiene standards and improve workforce productivity.

The robot’s autonomous capabilities include self-charging and automatic water refilling and discharge, reducing the need for continuous human intervention during routine operations. Its monitoring and reporting capabilities also provide facility operators with greater visibility into cleaning performance.

Built for demanding commercial environments, HYTRON addresses a practical operational need: helping facility operators maintain restroom hygiene while enabling cleaning teams to focus on other essential responsibilities.

Management Commentary

“As we expand HYTRON’s presence internationally, the United States remains a key market in our long-term growth strategy,” said Ken Ho, Chairman and Chief Executive Officer of Primech Holdings Limited.

“Through our MOU with Sunnytech, we are exploring opportunities to support HYTRON’s production and commercialisation in the U.S. This reflects our continued commitment to developing a scalable robotics business and creating long-term value for our shareholders.”

About Primech AI

Primech AI develops autonomous robotics solutions for the facilities services industry. Its flagship robot, HYTRON, combines AI-powered navigation and robotic manipulation to automate commercial restroom cleaning. Drawing on the Group’s facilities services experience, Primech AI focuses on practical automation that supports hygiene standards, workforce productivity and operational efficiency. For more information, visit https://primech.ai.

About Primech Holdings Limited

Primech Holdings Limited (Nasdaq: PMEC) is a Singapore-headquartered technology-driven facilities services and AI robotics group with operations in Singapore and Hong Kong. Through its subsidiaries, the Group provides cleaning, facilities maintenance, stewarding, waste management and pest control services to public and private sector clients.

Through its subsidiary Primech AI, the Group develops HYTRON, an autonomous restroom-cleaning robot that combines AI perception with robotic manipulation. The Group also operates HomeHelpy, a consumer home-services booking platform.

Primech Holdings was incorporated in 2020 and listed on the Nasdaq Capital Market in October 2023. For more information, visit investor.primechholdings.com.

Forward-Looking Statements

Certain statements in this announcement are forward-looking statements, including statements regarding the proposed collaboration with Sunnytech, the potential negotiation and execution of a definitive agreement, potential U.S.-based production and assembly activities, quality assurance, testing, certification, anticipated operational benefits, HYTRON’s U.S. commercialisation opportunities, international expansion, potential deployment and future growth. These statements involve known and unknown risks and uncertainties and are based on the Company’s current expectations, projections and assumptions. Forward-looking statements may be identified by words such as “may,” “will,” “expect,” “anticipate,” “aim,” “intend,” “plan,” “believe,” “potential” and similar expressions. Actual results may differ materially from those expressed or implied. The MOU is a non-binding statement of intent, and there can be no assurance that the proposed collaboration will result in a definitive agreement, manufacturing activities, successful certification or commercial deployment. Investors should review the risks and uncertainties described in the Company’s filings with the U.S. Securities and Exchange Commission. The Company undertakes no obligation to update or revise these statements except as required by law.

Investor Relations

Primech Holdings Limited
ir@primechholdings.com
www.primechholdings.com

CHICAGO, Oct. 21, 2026 (GLOBE NEWSWIRE) — XAI Floating Rate & Alternative Income Trust (NYSE: XFLT) (the “Fund”), announced today the final results of its Tender Offer (the “Tender Offer”), which commenced September 18, 2026, and expired at 11:59 p.m., Eastern Time, on October 19, 2026. The Tender Offer was for up to 1,903,861 (approximately 12.5%) of the Fund’s outstanding common shares of beneficial interest, par value $0.01 per share (“Common Shares”). The purchase price of validly tendered and accepted Common Shares for the Fund will be 98% of the Fund’s net asset value (“NAV”) as of the close of regular trading on the New York Stock Exchange on October 20, 2026.

The table below shows the final results of the Tender Offer as calculated by Computershare Trust Company, N.A. the depositary for the Tender Offer (the “Depositary”):

Tender Offer Amount	Shares Validly Tendered	Shares to be Purchased	Pro-Ration Factor*		Purchase Price of Validly Tendered Shares**		Number of Outstanding Common Shares after Giving Effect to Tender Offer
Up to 12.5% or 1,903,861 Shares	7,331,021	1,903,861	26.01%		$21.0602		13,327,023

* The number of Common Shares to be purchased divided by the number of Common Shares validly tendered. The pro-ration factor is subject to rounding adjustment to avoid the purchase of fractional shares.

** The purchase price of validly tendered and accepted Common Shares will be 98% of the Fund’s net asset value (“NAV”) as of the close of regular trading on the New York Stock Exchange on October 20, 2026.

Questions regarding the Tender Offer may be directed to Okapi Partners LLC, the Information Agent for the Tender Offer, who can be reached at the toll-free number (877) 796-5274.

About XA Investments

XA Investments LLC (“XAI”) is a Chicago-based firm founded by XMS Capital Partners in 2016. XAI serves as the investment adviser for two listed closed-end funds, an interval fund, and a tender offer fund. The listed closed-end funds, the XAI Floating Rate & Alternative Income Trust and XAI Madison Equity Premium Income Fund both trade on the New York Stock Exchange and the interval fund and tender offer fund, XAI CLO & Income Opportunities Fund and Evanston Multi-Alpha Fund are both available via direct subscription and through select broker/dealers and wealth management platforms.

In addition to investment advisory services, the firm also provides investment fund structuring and consulting services focused on registered closed-end funds to meet institutional client needs. XAI offers custom product build and consulting services, including product development and market research, marketing and fund management.

XAI believes that the investing public can benefit from new vehicles to access a broad range of alternative investment strategies and managers. XAI provides individual investors with access to institutional-caliber alternative managers. For more information, please visit www.xainvestments.com.

About XMS Capital Partners

XMS Capital Partners, LLC, established in 2006, is a global, independent, financial services firm providing M&A, corporate advisory and asset management services to clients. It has offices in Chicago, Boston and London. For more information, please visit www.xmscapital.com.

About Rockford Tower Asset Management

Rockford Tower Asset Management, L.L.C. is a wholly owned subsidiary of King Street Capital Management, L.P. (“King Street”) and an affiliate of Rockford Tower Capital Management (“Rockford Tower”). Rockford Tower, King Street’s dedicated CLO, CBO and SMA platform, was formed in 2017. Rockford Tower has over $14.7 billion of assets under management as of September 30, 2026, across 19 U.S. CLOs and 10 European CLOs, one CBO transaction and one SMA. In addition, Rockford Tower has traded over $99 billion of loans as of December 31, 2025.

About King Street Capital Management

King Street is a global alternative investment firm founded in 1995 that manages $30.9 billion in assets across public and private markets. The firm marries rigorous fundamental research with tactical trading and differentiated sourcing capabilities to identify investment opportunities across asset classes, up and down the capital structure. For more information, please visit www.kingstreet.com.

XAI does not provide tax advice; please consult a professional tax advisor regarding your specific tax situation. Income may be subject to state and local taxes, as well as the federal alternative minimum tax.

Investors should consider the investment objectives and policies, risk considerations, charges and expenses of the Fund carefully before investing. For more information on the Fund, please visit the Fund’s webpage at www.xainvestments.com.

This press release shall not constitute an offer to sell or a solicitation to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer or solicitation or sale would be unlawful prior to registration or qualification under the laws of such state or jurisdiction.

NOT FDIC INSURED		NO BANK GUARANTEE		MAY LOSE VALUE

Paralel Distributors, LLC – Distributor

Media Contact: 
Kimberly Flynn, President
XA Investments LLC
Phone: 888-903-3358
Email: KFlynn@XAInvestments.com
www.xainvestments.com

Subscription-based platform designed to help businesses compete for visibility on ChatGPT and Gemini, positioning Change Agents to capitalize on the shift toward AI-powered search

FREEHOLD, N.J., Oct. 21, 2026 (GLOBE NEWSWIRE) — Change Agents Corporation (Nasdaq: CHGA) (“Change Agents” or the “Company”), a technology company developing commercial agentic AI software through its wholly owned subsidiary, Avalon Quantum AI, LLC, and pursuing AI-enabled drone technologies through a separate wholly owned subsidiary, Autonomous Air Defense Systems LLC, today announced that it plans to commercially launch Beacon, a subscription-based Agentic Generative Search Optimization (GEO) platform designed to help small businesses improve their visibility across the five leading AI assistants; ChatGPT, Gemini, Perplexity, Grok and Claude.

The platform will go live on October 28, 2026, with additional information available at www.changeagentscorp.com/beacon/. Beacon is designed to help small businesses understand how they appear in AI-powered search results, identify opportunities to improve their online visibility, and attract potential customers.

Beacon has been developed to potentially address an emerging challenge for small businesses as consumers increasingly turn to AI assistants to discover local businesses, compare services, and make purchasing decisions, namely “Is AI recommending my business?”. Unlike traditional search engines, AI assistants can provide direct recommendations to consumers, creating a new competitive environment in which businesses need to understand whether they are being recommended and how they compare with competitors.

The platform deploys an AI agent to analyze a business’s online presence, customer reviews, reputation, and visibility across AI assistants. It then provides actionable recommendations designed to help business owners improve how their businesses are discovered and represented in AI-generated responses.

“AI is fundamentally changing how consumers discover businesses, yet most small business owners have little visibility into whether their companies are being recommended by AI assistants,” said Michael Mathews, Director of Change Agents Corp. “Beacon is designed to make this emerging technology accessible and affordable for small businesses. For just $20 per month, business owners can gain valuable insight into their AI visibility, understand how they compare with competitors, and identify practical steps to improve their online presence. We believe Beacon addresses a growing market need while establishing an opportunity for Change Agents to build a scalable, subscription-based software business.”

AI-Powered Visibility Audits and Subscription-Based Monitoring

Beacon is designed to provide small businesses with an accessible, straightforward process for understanding and improving their visibility across the leading AI assistants.

The platform’s principal features include:

• Free AI Visibility Audit: Following a simple registration and email verification process, Beacon’s AI agent conducts a free visibility audit in five minutes or less, evaluating the completeness of a business’s online profile, customer reviews and reputation, and how frequently AI assistants recommend the business relative to its major competitors.
• Competitive Visibility Analysis: The platform evaluates business recommendations across approximately 100 common customer queries, providing insight into how a business compares with competitors when potential customers use AI assistants to search for products and services.
• Full Visibility Report: For a subscription fee of $20 per month, business owners receive monthly detailed reports showing how customers and AI assistants discover their business, along with recommended improvements designed to strengthen online visibility and potentially increase customer traffic.
• On-Demand Visibility Monitoring: Subscribers can access and refresh their visibility reports as often as desired, enabling them to monitor changes in their AI search presence and competitive positioning over time.
• Optional Implementation Services: Following the full visibility report, subscribers can engage Beacon’s services team to implement recommended improvements on their behalf, providing an additional potential revenue opportunity beyond monthly subscriptions.

The Company believes Beacon’s combination of automated analysis, actionable recommendations, and affordable subscription pricing can help address a gap in the small business market, where sophisticated digital marketing and AI optimization services have historically been difficult or costly for smaller organizations to access.

Targeting the U.S. Small Business Market

Beacon is initially targeting an estimated 5.6 million U.S. small businesses with fewer than 50 employees, representing a substantial potential market for affordable AI-powered visibility and optimization services.

The Company’s go-to-market strategy will emphasize the platform’s free initial visibility audit, allowing business owners to evaluate their AI presence before deciding whether to subscribe to ongoing monitoring and optimization services.

Management believes this approach can support broad product awareness, encourage subscription conversion, and create opportunities for recurring revenue as Beacon’s customer base expands.

“We believe Beacon represents an attractive opportunity to translate the growing adoption of AI into a practical, revenue-generating application for millions of small businesses,” added Mathews. “Our initial focus will be on driving awareness and converting free audits into paid subscriptions. As adoption increases, we believe Beacon has the potential to become an important source of recurring SaaS revenue and further validate our broader agentic AI commercialization strategy.”

Beacon is scheduled to launch commercially on October 28, 2026, at www.thebeaconapp.com.

About Change Agents Corporation

Change Agents Corporation (Nasdaq: CHGA) is a developer of agentic artificial intelligence software solutions. The Company is expanding its strategy into AI-enabled autonomous air defense and counter-UAS technologies through its wholly owned subsidiary, Autonomous Air Defense LLC. Change Agents is evaluating technologies, strategic partnerships and acquisition opportunities intended to position the Company in markets where artificial intelligence, autonomous systems and advanced defense technologies converge. The Company’s current portfolio includes Beacon, an AI Search Optimization platform, and Catch-Up, an autonomous AI-powered content creation platform. Through its scalable Software-as-a-Service (SaaS) business model, Change Agents is focused on delivering innovative AI solutions that create measurable customer value while generating recurring subscription revenue and long-term shareholder returns. The Company is seeking to expand into various high growth sectors that are expected to benefit from artificial intelligence.

Change Agents is also distributing the KetoAir™ breathalyzer device a non-invasive consumer breathalyzer that measures ketosis levels and is sold in North America, which is registered with the U.S. Food and Drug Administration as a Class I medical device.

For more information about Change Agents Corp, please visit www.changeagentscorp.com.

Forward-Looking Statements

Forward-looking statements are made based on our expectations and beliefs concerning future events impacting the Company and therefore involve several risks and uncertainties. You can identify these statements by the fact that they use words such as “will,” “anticipate,” “estimate,” “expect,” “should,” “may,” “intend,” “plan,” “believe,” and other words and terms of similar meaning or references to future dates; however, the absence of these words or similar expressions does not mean that a statement is not forward-looking.

These statements include, but are not limited to, statements regarding the anticipated commercial launch of Beacon on October 28, 2026; the platform’s functionality, performance, capabilities, and anticipated benefits; the Company’s ability to successfully commercialize Beacon and attract small business customers; the size and potential of the U.S. small business market; the anticipated demand for AI-powered business visibility and Generative Engine Optimization solutions; the Company’s ability to convert free visibility audits into paid subscriptions; the potential to generate scalable recurring SaaS revenue and additional revenue from implementation services; the Company’s ability to establish partnerships with Chambers of Commerce and other small business organizations; the effectiveness of its customer acquisition and market penetration strategies; and the Company’s broader agentic AI development and commercialization plans.

Market data cited herein is derived from third-party sources that the Company believes to be reliable but has not independently verified. There can be no assurance that Beacon will launch on the anticipated date, achieve meaningful customer adoption, generate recurring subscription revenue, establish anticipated distribution partnerships, or realize the expected commercial benefits. The Company’s ability to successfully commercialize Beacon is subject to various risks, including technical and operational challenges, competition, customer acquisition and retention, changes in third-party AI platforms and search technologies, and the ability to develop and maintain commercially viable software solutions.

Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors disclosed in our filings with the SEC, accessible through the SEC’s website (www.sec.gov), including our most recent Annual Report on Form 10-K, Quarterly Reports on Form 10-Q, and Current Reports on Form 8-K filed or furnished with the SEC. In addition to these factors, actual future performance, outcomes, and results may differ materially because of more general factors, including, without limitation, general industry and market conditions and growth rates, technological developments, economic conditions, competitive pressures, and governmental and public policy changes.

The forward-looking statements included in this press release represent the Company’s views as of the date of this press release, and these views could change. The Company disclaims any obligation to update forward-looking statements, except as required by applicable law. These forward-looking statements should not be relied upon as representing the Company’s views as of any date subsequent to the date of this press release. The contents of any website referenced in this press release are not incorporated by reference herein.

Contact Information:
Change Agents Corp.
ir@changeagentscorp.com

Investor Relations:
Crescendo Communications, LLC
Tel: (212) 671-1020 Ext. 304
CHGA@crescendo-ir.com

GEORGE TOWN, Cayman Islands, Oct. 21, 2026 (GLOBE NEWSWIRE) — Consolidated Water Co. Ltd. (NASDAQ Global Select Market: CWCO), a leading designer, builder, and operator of advanced water treatment plants, today provided an update on permitting and the anticipated construction schedule for its Kalaeloa seawater reverse osmosis desalination project on Oahu, Hawaii.

Since the company’s previous update, the project received approval of its Preservation Plan and Archaeological Monitoring Plan from the State Historic Preservation Division and approval from the Hawaii Department of Health for a Substantial Modification to an Existing Regulated Public Water System. These approvals were required before the company could advance its applications for other permits and approvals.

Several permits and approvals remain outstanding, including a Memorandum of Agreement from the State Historic Preservation Division. Based on the current permitting timeline, Consolidated Water now expects construction to begin in the first half of 2027, compared with its previous expectation of late 2026. The Honolulu Board of Water Supply has granted schedule extensions to reflect the permitting process delays.

In July 2026, the Honolulu Board of Water Supply issued a limited notice to proceed authorizing approximately $6 million for the procurement of long-lead equipment. The early procurement is intended to reduce potential scheduling pressure once the remaining permits and approvals are obtained.

The Kalaeloa facility is being developed under Consolidated Water’s contract to design, build, operate, and maintain a seawater reverse osmosis desalination plant capable of producing 1.7 million gallons of potable water per day. Following commissioning, the company is contracted to operate and maintain the facility for 20 years, with two additional five-year extension options at the client’s discretion.

“We continue to make meaningful progress on the Kalaeloa desalination project,” said Consolidated Water CEO Rick McTaggart. “The recent approvals from the State Historic Preservation Division and the Hawaii Department of Health represent important steps in the permitting process and allow us to advance applications for the remaining permits and approvals. While the permitting timeline has shifted our anticipated construction start to the first half of 2027, the Honolulu Board of Water Supply continues to be supportive and has granted schedule extensions to reflect the process. The limited notice to proceed issued in July is also enabling us to procure long-lead equipment now, which should help the project advance efficiently once the remaining permits and approvals are in place.”

About Consolidated Water Co. Ltd.
Consolidated Water Co. Ltd. develops and operates advanced water treatment plants and water distribution systems. The company designs, constructs, and operates seawater desalination facilities in the Cayman Islands, The Bahamas, and the British Virgin Islands, and designs, constructs, and operates water treatment and reuse facilities in the United States.

The company also manufactures and services a wide range of products and provides design, engineering, management, operating, and other services applicable to commercial and municipal water production, supply and treatment, and industrial water and wastewater treatment.

For more information, visit cwco.com.

Cautionary Note Regarding Forward-Looking Statements

This press release includes statements that may constitute “forward-looking” statements, usually containing the words “believe,” “estimate,” “project,” “intend,” “expect,” “should,” “will” or similar expressions. This press release contains, or may be deemed to contain, “forward-looking statements” (as defined in the U.S. Private Securities Litigation Reform Act of 1995), including statements regarding the anticipated construction schedule and completion of the Kalaeloa desalination facility; the effect of permitting delays on that schedule; the timing and receipt of the remaining permits and approvals; the company’s and the Honolulu Board of Water Supply’s efforts to mitigate those delays; and the company’s ability to perform its design, build, operate, and maintain obligations with respect to the Kalaeloa facility, including the anticipated 20-year operating term and any exercise of the related extension options. These statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements inherently involve risks and uncertainties that could cause actual results to differ materially from the forward-looking statements. Factors that would cause or contribute to such differences include, but are not limited to, (i) continued acceptance of the company’s products and services in the marketplace; (ii) changes in its relationships with the governments and clients of the jurisdictions in which it operates, including the Honolulu Board of Water Supply; (iii) the timing and outcome of permitting and other regulatory approvals affecting the Kalaeloa facility; (iv) the company’s ability to procure equipment and perform its contractual obligations on the anticipated timeline and budget, including with respect to the Kalaeloa facility and the Florida purchase orders; (v) changes in demand, consumption levels, operating costs, energy costs, weather, and economic conditions in the jurisdictions in which the company operates; and (vi) various other risks such as economic, operational, and industry-specific risks, as detailed in the company’s periodic report filings with the Securities and Exchange Commission (“SEC”). For more information about risks and uncertainties associated with the company’s business, please refer to the “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and “Risk Factors” sections of the company’s SEC filings, including, but not limited to, its annual report on Form 10-K and quarterly reports on Form 10-Q, copies of which may be obtained by contacting the company’s Secretary at the company’s executive offices or at the “Investors – SEC Filings” page of the company’s website at ir.cwco.com/docs. Except as otherwise required by law, the company undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise.

Company Contact:
David W. Sasnett
Executive Vice President and CFO
Tel (954) 509-8200
Email Contact

Investor & Media Contact:
Ron Both or Grant Stude
Encore Investor Relations
Tel (949) 432-7450
Email Contact

Milestone moves Firefly’s Elytra spacecraft toward final design and hardware production to deliver NASA JPL drones above the lunar south pole

CEDAR PARK, Texas, Oct. 21, 2026 (GLOBE NEWSWIRE) — Firefly Aerospace (Nasdaq: FLY), a market leading space and defense technology company, today announced it completed the preliminary design review (PDR) for its Elytra spacecraft that will deliver drones built by NASA’s Jet Propulsion Laboratory (JPL) to the Moon’s south pole for the agency’s MoonFall mission.

Firefly’s PDR, including members from NASA and JPL, conducted a thorough review of Elytra’s structural, thermal, propulsion, avionics, trajectory design, guidance and navigation, communications and control systems as well as the spacecraft’s qualification and environmental test plans. The review confirmed Elytra’s design meets the mission requirements, and Firefly will now begin working toward the spacecraft’s final critical design review (CDR) ahead of hardware production and assembly.

“Completing PDR less than four months after contract award is a testament to the speed and rigor Firefly brings to every mission,” said Ray Allensworth, Vice President of Spacecraft at Firefly Aerospace. “As NASA accelerates its Moon Base Program, we’re rapidly scaling spacecraft production to support MoonFall and a growing manifest of lunar surface missions, utilizing proven systems, hardware, and operations from our first successful Blue Ghost mission.”

Targeted to be ready for launch by late 2028, MoonFall is part of the first phase of the Moon Base, a long-term lunar exploration and infrastructure initiative designed to enable sustained human presence and expanded scientific and commercial activity at the lunar south pole.

JPL is building the drones and managing the mission for NASA, which will source the launch vehicle for MoonFall. After launching, Firefly’s Elytra spacecraft will transit from Earth orbit to lunar orbit and deploy the drones above the Moon’s south pole. The MoonFall drones will then use their high-definition optical cameras and instruments to survey the south pole terrain and map safe landing spots and resources to support future human missions.

About Firefly Aerospace
Firefly Aerospace is a space and defense technology company on a mission to reliably and repeatedly launch, land, and operate space systems from Earth to the Moon and beyond. As the partner of choice for responsive space missions, Firefly is the first commercial company to launch a satellite to orbit with approximately 24-hour notice and the first to achieve a successful landing on the Moon. Established in 2017, Firefly’s engineering, manufacturing, and test facilities are co-located in central Texas to enable rapid innovation and vertical integration for the company’s small- to medium-lift launch vehicles, lunar landers, and orbital vehicles. For more information, visit www.fireflyspace.com.

Forward-Looking Statement
This press release contains “forward-looking statements” including, but not limited to, statements regarding timing of the MoonFall mission, Elytra and drone performance specifics and capabilities, statements of Firefly’s Vice President of Spacecraft, and other statements regarding Firefly’s future expectations, beliefs, plans, objectives, financial condition, assumptions, future events, or performance that are not historical facts. In some cases, you can identify forward-looking statements because they contain words such as “allows” “enable,” “may,” “position,” “will,” “expects,” “plans,” “anticipates,” “could,” “would,” “target”, “set,” “intends,” “support,” and “believes.” There may also be negative words or other similar terms or expressions that concern our expectations, strategy, plans, or intentions. Not all forward-looking statements contain such identifying words. The inclusion of forward-looking statements should not be regarded as a representation that such plans, estimates, or expectations will be achieved.

Various risks that could cause actual results to differ from those expressed by the forward-looking statements included in this press release include, but are not limited to: our failure to manage our growth effectively, including the increasing technological complexity of our business, and our ability to achieve and maintain profitability; the potential for delayed or failed launches, and any failure of our launch vehicles and spacecraft to operate as intended; our inability to deliver software on time or of a quality that our customers demand; the hazards and operational risks that our products and service offerings are exposed to, including the wide and unique range of risks due to the unpredictability of space; the inability to realize our backlog; the fluctuation of our operating results; adverse publicity stemming from any incident involving us, our competitors, or our customers; the failure to adequately protect our proprietary intellectual property rights; our inability to comply with our contractual obligations; and other risk factors set forth in our filings with the Securities and Exchange Commission.

Readers are cautioned not to place undue reliance on the forward-looking statements contained herein, which speak only as of the date hereof. These statements are based on management’s current expectations, assumptions, and beliefs concerning future developments, which are inherently subject to uncertainties, risks, and changes in circumstances that are difficult to predict. We cannot assure you that the events reflected in the forward-looking statements will occur; actual events could differ materially from those described in the forward-looking statements. We undertake no intent or obligation to publicly update or revise any of the estimates and other forward-looking statements made in this announcement, whether as a result of new information, future events or otherwise, except as required by law.

Media Contact
press@fireflyspace.com

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/566d99b1-e944-4d41-9c79-df910efa5210

MALVERN, Pa., Oct. 21, 2026 (GLOBE NEWSWIRE) — Neuronetics, Inc. (NASDAQ: STIM), a leader in interventional mental health that combines its NeuroStar® TMS technology with direct patient care through the Greenbrook network of interventional psychiatry clinics, today announced that it plans to release third quarter 2026 financial and operating results prior to market open on Wednesday, November 4, 2026. The Company will host a conference call to review its results at 8:30 a.m. Eastern Time the same day.

The conference call will be broadcast live in listen-only mode via webcast at Neuronetics Q3 2026 Earnings. To listen to the conference call on your telephone, participants may register for the call here. While it is not required, it is recommended you join 10 minutes prior to the event start.

About Neuronetics

Neuronetics, Inc. is a leader in interventional mental health, combining innovative treatment technologies with direct patient care. Through its NeuroStar® Advanced Therapy system, the company is a leading provider of transcranial magnetic stimulation (TMS) treatment and, through Greenbrook, operates one of the largest interventional psychiatry clinic networks in the United States, offering both TMS and SPRAVATO® therapies. NeuroStar Advanced Therapy is a non-drug, noninvasive treatment that can improve the quality of life for people suffering from neurohealth conditions when traditional medication has not helped. NeuroStar Advanced Therapy is the leading TMS treatment for MDD in adults and is backed by what we believe is the largest clinical data set of any TMS treatment system for depression. Greenbrook treatment centers also offer SPRAVATO® (esketamine) Nasal Spray, a prescription medicine indicated for the treatment of treatment-resistant depression (“TRD”) in adults as monotherapy or in conjunction with an oral antidepressant. It is also indicated for depressive symptoms in adults with MDD with acute suicidal ideation or behavior in conjunction with an oral antidepressant.¹

The NeuroStar Advanced Therapy System is cleared by the U.S. Food and Drug Administration for adults with MDD, as an adjunct for adults with obsessive-compulsive disorder, to decrease anxiety symptoms in adult patients with MDD that may exhibit comorbid anxiety symptoms (anxious depression), and as a first line adjunct for the treatment of MDD in adolescent patients aged 15-21. For safety information and indications for use, visit NeuroStar.com.

Investor Contact:
Mark Klausner
ICR Healthcare
443-213-0499
ir@neuronetics.com

Media Contact:
EvolveMKD
646-517-4220
NeuroStar@evolvemkd.com

References

1 The effectiveness of SPRAVATO® in preventing suicide or in reducing suicidal ideation or behavior has not been demonstrated. Use of SPRAVATO® does not preclude the need for hospitalization if clinically warranted, even if patients experience improvement after an initial dose of SPRAVATO®. For more important safety information about SPRAVATO®, please visit spravatohcp.com.

Phase 1 results demonstrate TMB-365 antiviral activity and tolerability, supporting continued development as a differentiated antibody for combination HIV treatment

Complementary laboratory susceptibility findings support the scientific rationale for the TMB-365/TMB-380 antibody-only maintenance regimen

TAIPEI, Taiwan, Oct. 21, 2026 (GLOBE NEWSWIRE) — TaiMed Biologics (TPEX: 4147), a commercial-stage CD4-targeted biologics company advancing antibody-based therapies for long-acting HIV treatment, today announced results from two studies to be presented at IDWeek 2026, October 21-24 in Washington, D.C. The findings highlight TMB-365’s own clinical activity and potential as a component of multiple long-acting HIV combinations, alongside laboratory evidence of complementary antiviral susceptibility supporting the company’s TMB-365/TMB-380 maintenance regimen.

“These data reinforce our view of TMB-365 as a differentiated antibody with potential across multiple long-acting HIV combinations,” said Jimmy Chang, Ph.D., Chief Executive Officer of TaiMed Biologics. “Its host-directed mechanism, antiviral activity and pharmacokinetic profile provide a foundation for exploring combinations with other antibodies and small-molecule antiretrovirals. TMB-365/TMB-380 is our most advanced application of this approach, and the susceptibility findings strengthen the scientific rationale for pairing these two antibodies.”

TMB-365: Clinical activity and a distinct role in future HIV combinations

TMB-365 is an investigational, second-generation monoclonal antibody derived from ibalizumab. It binds domain 2 of the CD4 receptor on host cells and inhibits HIV entry after attachment, providing a mechanism distinct from antibodies that target the virus directly. TMB-365 was engineered to improve the breadth of antiviral coverage and pharmacokinetics relative to ibalizumab. TaiMed is developing TMB-365 as a distinct antibody asset for use in combination HIV regimens.

The randomized, placebo-controlled Phase 1 study (NCT04027387) evaluated single intravenous doses of 400, 800 and 1,600 mg in 25 people living with HIV over 10 weeks. The lower-dose cohorts included participants with detectable HIV who were off antiretroviral therapy; the 1,600-mg cohort remained on stable combination antiretroviral therapy with suppressed HIV. Key findings included:

• Antiviral activity: Mean maximum HIV-1 RNA reductions were 1.55 and 1.57 log10 copies/mL at 400 and 800 mg, respectively. Antiviral effects were observed for up to two and four weeks, respectively.
• Tolerability: No serious treatment-emergent adverse events, Grade 3 or higher events, or adverse-event-related discontinuations were observed. All 23 treatment-emergent events were mild or moderate; six events in three participants were considered related to TMB-365. No anti-drug antibodies were observed.
• Target engagement and dosing potential: In a limited subset, mean CD4 receptor occupancy remained at or above 80% for five to six weeks at 800 and 1,600 mg. The pharmacokinetic findings support further evaluation of higher doses and dosing intervals of eight to 12 weeks.
• Resistance observations: No resistance or cross-resistance to TMB-365 or approved entry inhibitors was observed during the study.

Together, these results support continued development of TMB-365 beyond a single antibody pairing. Its host-directed mechanism and engineered properties provide a rationale for exploring combinations with complementary antibodies and long-acting small-molecule antiretrovirals. The safety, efficacy and dosing of such future combinations will require clinical evaluation.

TMB-365/TMB-380: Complementary susceptibility supports combination development

The second presentation reports laboratory susceptibility findings for TMB-365 and TMB-380, a broadly neutralizing antibody that targets the CD4-binding site on the HIV envelope protein gp120. Researchers evaluated a panel of 40 HIV pseudotypes: 20 susceptible to TMB-380 and 20 with reduced susceptibility or resistance to TMB-380. They also studied a laboratory-selected virus resistant to LM52, a precursor of TMB-365.

• TMB-365 retained activity against variants less susceptible to TMB-380: Its geometric mean IC50 was similar in the TMB-380-susceptible and reduced-susceptibility groups: 0.054 and 0.057 micrograms/mL, respectively. Of the 20 variants with reduced susceptibility or resistance to TMB-380, 19 were susceptible to TMB-365; one showed incomplete neutralization, with a maximum inhibition of 70%.
• Complementary activity was also seen in the precursor experiment: The LM52-resistant virus became more susceptible to VRC-07 and VRC-01, antibodies related to TMB-380, supporting the hypothesis that the two mechanisms may cover different viral susceptibility gaps.

These in vitro findings support a complementary-activity hypothesis for TMB-365/TMB-380. Their clinical implications for durable viral suppression and resistance outcomes require further study.

“The Phase 1 findings demonstrate TMB-365’s antiviral activity in people living with HIV, while the laboratory study helps explain why its host-directed mechanism could complement a virus-directed antibody,” said Martin Markowitz, M.D., Medical Director of TaiMed Biologics and presenting author of both studies. “TMB-365’s activity against variants with reduced susceptibility to TMB-380 is encouraging. Further clinical studies will determine whether that complementarity translates into durable viral suppression and favorable resistance outcomes.”

TMB-365/TMB-380 is being evaluated as an antibody-only maintenance regimen for virologically suppressed people living with HIV. In the earlier 20-participant Phase 2a study, dosing every eight weeks over 24 weeks produced no protocol-defined virologic failures among participants who completed treatment. An ongoing Phase 2b study is evaluating the regimen against continued oral antiretroviral therapy, with interim results expected by year-end 2026.

IDWeek 2026 presentation details

Oral Presentation 
Title: Single-dose escalation study of TMB-365 in people living with HIV: safety, pharmacokinetics, and antiviral activity.
Date & Time: Friday, October 23, 2:45-2:57 p.m. ET
Session: Hot Off the Press: New Pathways in HIV Treatment
Location: Room 103 AB

Poster Presentation
Title: TMB-365 and TMB-380: A potentially resistance repellant stand-alone maintenance bNAb regimen in suppressed people living with HIV-1 on combination antiretroviral therapy.
Date & Time: Thursday, October 22, 12:15-1:30 p.m. ET
Session: Resistance Mechanisms
Location & Poster Code: Poster Hall B-C, Poster P-82

About TaiMed Biologics
Founded in 2007, TaiMed Biologics (TPEX: 4147) is a leading commercial-stage biotechnology company focused on developing innovative therapies for HIV treatment. The company developed ibalizumab (Trogarzo^®), the first monoclonal antibody approved by the U.S. FDA for the treatment of HIV-1, and is advancing TMB-365/380, its lead clinical-stage long-acting maintenance therapy candidate for people living with HIV. TaiMed Biologics also offers comprehensive contract development and manufacturing (CDMO) services. Its shares trade on the Taipei Exchange.

Forward-Looking Statements
This press release contains forward-looking statements, including statements about the presentation of data at IDWeek 2026 and the development and potential of TMB-365, TMB-380, and the TMB-365/TMB-380 regimen. These statements are based on current expectations and involve risks and uncertainties, including those related to clinical development, regulatory review, and commercialization, that could cause actual results to differ materially. Forward-looking statements speak only as of the date of this release, and TaiMed Biologics undertakes no obligation to update them except as required by law.

Contacts

Investor Relations
Kenny Lin
hlin@taimedbio.com

Media
Mike Tattory
LifeSci Communications
mtattory@lifescicomms.com